Oxalosuccinic acid

Oxalosuccinic acid
Oxalosuccinic acid
IUPAC name
1-Oxopropane-1,2,3-tricarboxylic acid
Identifiers
CAS number 1948-82-9
PubChem 972
Jmol-3D images Image 1
Properties
Molecular formula C6H6O7
Molar mass 190.11 g mol−1
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Oxalosuccinic acid is a substrate of the citric acid cycle. It is acted upon by isocitrate dehydrogenase. Salts and esters of oxalosuccinic acid are known as oxalosuccinates.


v · d · eCitric Acid Cycle Metabolic Pathway
Oxaloacetate Malate Fumarate Succinate Succinyl-CoA
Oxaloacetate wpmp.png S-malate wpmp.png Fumarate wpmp.png Succinate wpmp.png Succinyl-CoA wpmp.png
Biochem reaction arrow reverse NNYY horiz med.png Biochem reaction arrow reverse NNYN horiz med.png Biochem reaction arrow reverse NNYY horiz med.png Biochem reaction arrow reverse NNYY horiz med.png
Acetyl-CoA NADH + H+ NAD+ H2O FADH2 FAD CoA + ATP(GTP) Pi + ADP(GDP)
Acetyl co-A wpmp.png + H2O Biochem reaction arrow special 1.png Biochem reaction arrow special 2.png NADH + H+ + CO2
CoA NAD+
Citrate wpmp.png H2O Cis-Aconitate wpmp.png H2O Threo-Ds-isocitrate wpmp.png NAD(P)+ NAD(P)H + H+ Oxalosuccinate wpmp.png CO2 2-oxoglutarate wpmp.svg
Biochem reaction arrow foward NYNN horiz med.png Biochem reaction arrow foward YNNN horiz med.png Biochem reaction arrow foward YYNN horiz med.png Biochem reaction arrow foward NYNN horiz med.png
Citrate cis-Aconitate Isocitrate Oxalosuccinate α-Ketoglutarate

M: MET

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)



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Look at other dictionaries:

  • oxalosuccinic acid — The product of the dehydrogenation of isocitric acid under the catalytic influence of isocitrate dehydrogenase; an enzyme bound intermediate of the tricarboxylic acid cycle. * * * ox·a·lo·suc·cin·ic acid äk sə lō sək .sin ik , äk sal ō …   Medical dictionary

  • oxalosuccinic acid — “+... noun Etymology: oxal + succinic : a tricarboxylic acid HOOCCOCH(COOH)CH2COOH recognized as an intermediate stage in the metabolism of fats and carbohydrates * * * /ok seuh loh seuhk sin ik, ok , ok sal oh , sal /, Biochem. an organic acid,… …   Useful english dictionary

  • oxalosuccinic acid — /ok seuh loh seuhk sin ik, ok , ok sal oh , sal /, Biochem. an organic acid, C6H6O7, that is an intermediate formed by the dehydrogenation of isocitric acid in fat and carbohydrate metabolism. [1920 25; OXAL(IC) + O + SUCCINIC ACID] * * * …   Universalium

  • oxalosuccinic acid — noun Etymology: oxalic + succinic acid Date: 1925 a tricarboxylic acid C6H6O7 that is formed as an intermediate in the Krebs cycle …   New Collegiate Dictionary

  • cycle — 1. A recurrent series of events. 2. A recurring period of time. 3. One successive compression and rarefaction of a wave, as of a sound wave. [G. kyklos, circle] anovulatory c. a …   Medical dictionary

  • isocitrate — A salt or ester of isocitric acid. i. dehydrogenase one of two enzymes that catalyze the conversion of threo ds i., the product of the action of both aconitase and i. lyase, to α ketoglutarate (2 oxoglutarate) and CO2; one of the isozymes uses …   Medical dictionary

  • oxal- — combining form or oxalo Etymology: French, from (acide) oxalique oxalic acid : related to oxalic acid oxalamide oxalosuccinic …   Useful english dictionary

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