Mycobacterium intracellulare

Mycobacterium intracellulare
Mycobacterium intracellulare
Scientific classification
Kingdom: Bacteria
Phylum: Actinobacteria
Order: Actinomycetales
Suborder: Corynebacterineae
Family: Mycobacteriaceae
Genus: Mycobacterium
Species: M. intracellulare
Binomial name
Mycobacterium intracellulare
Runyon 1965,[1] ATCC 13950

Mycobacterium intracellulare is a species of Mycobacterium.

Contents

Description

"Gram-positive", nonmotile and acid-fast short to long rods.

Colony characteristics

  • Usually smooth, rarely rough and nonpigmented colonies. Ageing colonies may become yellow.

Physiology

Differential characteristics

  • M. intracellulare and Mycobacterium avium form the M. avium-intracellulare complex (MAIC). A commercially available hybridisation assay (AccuProbe) to identify all members of the MAIC exists. Furthermore, separate AccuProbes are available to identify either M. intracellulare or M. avium.
  • Remarkable ITS heterogeneity within different M. intracellulare isolates.

Pathogenesis

  • Most frequently encountered in pulmonary secretions from patients suffering from tuberculosis-like disease and from surgical specimens from such patients.
  • When isolated from human secretions, it is often the etiologic agent of pulmonary disease, although frequently isolated as apparent casual resident
  • Biosafety level 2

Type strain

  • First isolated from fatal systemic disease in a child. Found in soil and water.

Strain ATCC 13950 = CCUG 28005 = CIP 104243 = DSM 43223 = JCM 6384 = NCTC 13025.

References

  1. ^ Runyon, E. 1965. Pathogenic mycobacteria. Advances in Tuberculosis Research, 14, 235-287.
  • Cuttino, J., A. McCabe. 1949. Pure granulomatous nocardiosis: A new fungus disease distinguished by intracellular parasitism. American Journal of Clinical Pathology, 25, 1-34.
v · d · eActinobacteria (high-G+C) Infectious diseases · Bacterial diseases: G+ (primarily A00–A79, 001–041, 080–109)
Actinomycineae
Actinomyces israelii (Actinomycosis, Cutaneous actinomycosis) · Tropheryma whipplei (Whipple's disease) · Arcanobacterium haemolyticum (Arcanobacterium haemolyticum infection)
Corynebacterineae
Tuberculosis: Ghon focus/Ghon's complex · Pott disease · brain (Meningitis, Rich focus) · Tuberculous lymphadenitis (Tuberculous cervical lymphadenitis) · cutaneous (Scrofuloderma, Erythema induratum, Lupus vulgaris, Prosector's wart, Tuberculosis cutis orificialis, Tuberculous cellulitis, Tuberculous gumma) · Lichen scrofulosorum · Tuberculid (Papulonecrotic tuberculid) · Primary inoculation tuberculosis · Miliary · Tuberculous pericarditis · Urogenital tuberculosis · Multi-drug-resistant tuberculosis · Extensively drug-resistant tuberculosis
Leprosy: Tuberculoid leprosy · Borderline tuberculoid leprosy · Borderline leprosy · Borderline lepromatous leprosy · Lepromatous leprosy · Histoid leprosy
R1: M. kansasii · M. marinum (Aquarium granuloma)
R3: M. avium complex/Mycobacterium avium/Mycobacterium intracellulare/MAP (MAI infection) · M. ulcerans (Buruli ulcer) · M. haemophilum
Bifidobacteriaceae
Gardnerella vaginalis

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)


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