- Mycobacterium heidelbergense
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Mycobacterium heidelbergense Scientific classification Kingdom: Bacteria Phylum: Actinobacteria Order: Actinomycetales Suborder: Corynebacterineae Family: Mycobacteriaceae Genus: Mycobacterium Species: M. heidelbergense Binomial name Mycobacterium heidelbergense
Haas et al. 1998, ATCC 51253Mycobacterium heidelbergense is a Gram-positive, nonmotile, acid-fast, coccobacilli.
Contents
Description
Dimensions : 0.5-0.8 µm x 2.0-3.0 µm
Colony characteristics
- Smooth, dome-like and nonpigmented colonies on Löwenstein-Jensen media at 35°C (0.5–1 mm in diameter).
- Slow growth on Löwenstein-Jensen medium at 35°C within 3–4 weeks.
- Optimal growth at a temperature range from 33°C to 35°C, but also growth at 30°C and 37°C, neither growth at 25°C nor at 45°C.
- Susceptible to isoniazid, rifampicin and ethambutol.
- Resistant to pyrazinamide and cycloserine.
Differential characteristics
- Differentiation from M. malmoense, (bearing a strong phenotypic resemblance to M. heidelbergense), by its wider range of susceptibility to antituberculous drugs, (including isoniazid), and by its inability to grow on Löwenstein-Jensen medium at 25°C.
- Differentiation of M. triplex from M. heidelbergense by its positive nitrate reduction test and by its characteristic HPLC profile (triple-mycolate pattern).
Pathogenesis
- Cervical lymphadenitis in immunocompetent patients.
- Biosafety level not known
Type strain
- First isolated from a immunocompetent paediatric patient with cervical lymphadenitis with recurrent fistula formation, in Heidelberg, Germany.
Strain 2554/91 = ATCC 51253 = CIP 105424 = DSM 44471.
References
- Haas et al. 1997. A new agent of mycobacterial lymphadenitis in children: Mycobacterium heidelbergense sp. nov. J. Clin. Microbiol. 35, 3203-3209.
Slowly growing
(R1P=photochromogenic;
R2S=scotochromogenic;
R3N=nonchromogenic)Rapidly growing/
Runyon IVM. neoaurum groupF/T groupsM. fortuitum groupM. vaccae groupM. smegmatis groupM. chelonae groupM. elephantis groupThis Mycobacterium article is a stub. You can help Wikipedia by expanding it.