- Ghon focus
A Ghon focus is a primary lesion caused by mycobacterium
bacilli( tuberculosis) developed in the lung of a previously uninfected individual. It is named for Anton Ghon( 1866- 1936), an Austrian pathologist.
It is a small area of granulomatous inflammation, only detectable by
chest X-rayif it calcifies or grows substantially (see tuberculosis radiology) Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; & Mitchell, Richard N. (2007). "Robbins Basic Pathology" (8th ed.). Saunders Elsevier. pp. 516-522 ISBN 978-1-4160-2973-1] . Typically these will heal, but in some cases, especially in immunosuppressed patients, it will progress to miliary tuberculosis(so named due to the calcified granulomas resembling milletseeds on a chest X-ray).
The classical location for primary infection is surrounding the lobar fissures, either in the upper part of the lower lobe or lower part of the upper lobe.
If the Ghon focus also involves infection of surrounding
lymph nodes, it is known as the Ghon's complexor primary complex [http://www.smbs.buffalo.edu/pth600/IMC-Path/y2case/y2ans10.htm] .
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