- Ghon focus
A Ghon focus is a primary lesion caused by mycobacterium
bacilli (tuberculosis ) developed in the lung of a previously uninfected individual. It is named forAnton Ghon (1866 -1936 ), an Austrianpathologist .It is a small area of granulomatous inflammation, only detectable by
chest X-ray if it calcifies or grows substantially (seetuberculosis radiology ) Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; & Mitchell, Richard N. (2007). "Robbins Basic Pathology" (8th ed.). Saunders Elsevier. pp. 516-522 ISBN 978-1-4160-2973-1] . Typically these will heal, but in some cases, especially in immunosuppressed patients, it will progress tomiliary tuberculosis (so named due to the calcified granulomas resemblingmillet seeds on a chest X-ray).The classical location for primary infection is surrounding the lobar fissures, either in the upper part of the lower lobe or lower part of the upper lobe.
If the Ghon focus also involves infection of surrounding
lymph nodes , it is known as theGhon's complex or primary complex [http://www.smbs.buffalo.edu/pth600/IMC-Path/y2case/y2ans10.htm] .References
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