Osmotic fragility

Osmotic fragility
Osmotic fragility
MeSH D009996

In hematology, osmotic fragility refers to the degree of hemolysis when red blood cells are placed in a hypotonic solution. In general, osmotic fragility is inversely proportional to the cell's surface-area-to-volume.[1][2][3]


  1. ^ Rodak, Bernadette F. et al. (2007). Hematology: clinical principles and applications. Elsevier Health Sciences. p. 291. ISBN 9781416030065. http://books.google.com/books?id=6sfacydDNsUC&pg=PA291. 
  2. ^ Fischbach, Frances Talaska & Dunning, Marshall Barnett (2008). A manual of laboratory and diagnostic tests (8th ed.). Lippincott Williams & Wilkins. p. 116. ISBN 9780781771948. http://books.google.com/books?id=CQuBkXDspBkC&pg=PA116. 
  3. ^ Greer, John P. et al., ed (2008). Wintrobe's clinical hematology. Lippincott Williams & Wilkins. p. 805. ISBN 9780781765077. http://books.google.com/books?id=68enzUD7BVgC&pg=PA805. 

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