- Cortisol O-acetyltransferase
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cortisol O-acetyltransferase Identifiers EC number 2.3.1.27 CAS number 9076-48-6 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a cortisol O-acetyltransferase (EC 2.3.1.27) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + cortisol
CoA + cortisol 21-acetate
Thus, the two substrates of this enzyme are acetyl-CoA and cortisol, whereas its two products are CoA and cortisol 21-acetate.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:cortisol O-acetyltransferase. Other names in common use include cortisol acetyltransferase, corticosteroid acetyltransferase, and corticosteroid-21-O-acetyltransferase.
References
- Thomas PJ (1968). "Cortisol acetyltransferase from baboon brain". Biochem. J. 109 (4): 695–6. PMC 1186958. PMID 4971640. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1186958.
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