Schistocyte

Peripheral blood (MGG stain): patient with hemolytic-uremic syndrome

A schistocyte or schizocyte (from Greek schistos for "divided" or schistein for "to split", and kytos for "hollow" or "cell") is a fragmented part of a red blood cell. Schistocytes are typically irregularly shaped, jagged, and asymmetrical. A true schistocyte does not have central pallor. ^[1] Schistocytes are sometimes referred to as "helmet cells."

Several microangiopathic diseases, including disseminated intravascular coagulation and thrombotic microangiopathies, generate fibrin strands that sever red blood cells as they try to move past a thrombus, creating schistocytes.

Schistocytes are often seen in patients with hemolytic anemia. They are frequently a consequence of mechanical heart valve prostheses. (See artificial heart valve)

Excessive schistocytes present in blood can be a sign of microangiopathic hemolytic anemia (MAHA) where the most common cause is aortic stenosis.

References

1. ^ Amanda Cox et al., Schistocytes: A Brief Overview. Retrieved 23 August 2008.

Lymphocytes

Smudge cell · Downey cell

Small molecules

Blood sugar	Hyperglycemia · Prediabetes (Impaired fasting glucose, Impaired glucose tolerance)
Nitrogenous	Azotemia · Hyperuricemia · Hypouricemia

Proteins

LFT	Elevated transaminases · Elevated ALP · Hypoproteinemia (Hypoalbuminemia)
Other	Elevated cardiac markers · Elevated alpha-fetoprotein

Minerals

Iron overload disorder

Pathogens/sepsis

Bacteremia · Viremia · Fungemia · Parasitemia · Algaemia

M: MYL cell/phys (coag, heme, immu, gran), csfs rbmg/mogr/tumr/hist, sysi/epon, btst drug (B1/2/3+5+6), btst, trns

M: URI anat/phys/devp/cell noco/acba/cong/tumr, sysi/epon, urte proc/itvp, drug (G4B), blte, urte