- Fungemia
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MeshID = D016469Fungemia (also known as Candidemia, Candedemia, and Invasive Candidiasis) is the presence of fungi or
yeasts in theblood . It is most commonly seen inimmunosuppressed orimmunocompromised patient s with severeneutropenia ,oncology patients, or in patients with intravenouscatheter s. Recently, it has been suggested the otherwise immunocompetent patients takinginfliximab may be at a higher risk for fungemia.The
diagnosis is complicated, as routineblood culture s have poor sensitivity.Treatment
Treatment involves use of
antifungals , e.g.fluconazole oramphotericin .Risk factors
The two most important risk factors are:
* Use of
broad-spectrum antibiotic s
* Colonization by fungi (see e.g.candidiasis )Other risk factors are:
*
Dialysis
*Diabetes
* Lowered intestinal flora
* SuppressedImmune system
*Central venous catheter
* High severity of illness
* Multipleabdominal surgeries
* Use ofsteroid s
* burnsPathogens
The most commonly known
pathogen is "Candida albicans ", causing roughly 70% of fungemias, followed by "Candida glabrata " with 10%, and "Aspergillus " with 1%. However, the frequency of infection by "T. glabrata", "Candida tropicalis ", "C. krusei", and "C. parapsilosis" is increasing, especially when significant use offluconazole is common.ymptoms
Symptoms can range from mild to extreme, often described as extreme
flu -like symptoms. Pain, mental disorders, chronic fatigue,infections , are a few of the long list of associated symptoms with Fungemia.See also
*
Bacteremia
*Candidiasis
*Mycosis External links
* [http://www.mc.vanderbilt.edu/surgery/trauma/egs/EGSProtocols/treatment%20of%20fungal%20infe.pdf Treatment of fungal infections]
* [http://www.doctorfungus.org/mycoses/human/candida/Candida_index.htm Candidiasis: Overview and Full Index]
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