- Nevus of Ota
-
Nevus of Ota Classification and external resources ICD-10 D22.3 (ILDS D22.301) DiseasesDB 32588 eMedicine DERM/290 MeSH D009507 Nevus of Ota (also known as "congenital melanosis bulbi,"[1] "nevus fuscoceruleus ophthalmomaxillaris," "oculodermal melanocytosis",[2]:700 and "Oculomucodermal melanocytosis"[1]) is a blue hyperpigmentation[3] that occurs on the face. It was first reported by Dr. M. T. Ota of Japan in 1939.[4]
Nevus of Ota is caused by the entrapment of melanocytes in the upper third of the dermis. It is found on the face unilaterally and involves the first two branches of the trigeminal nerve. The sclera is involved in two-thirds of cases (causing an increased risk of glaucoma). It should not be confused with Mongolian spot, which is a birthmark caused by entrapment of melanocytes in the dermis but is located in the lumbosacral region. Women are nearly five times more likely to be affected than men, and it is rare among white people. Nevus of Ota may not be congenital, and may appear during puberty.
Treatment
Q-switched laser has been used for treatment.[5][6]
Hydroquinone preparations are also helpful in partially treating this defect.
See also
References
- ^ a b Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1720–22. ISBN 1-4160-2999-0.
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ^ Chan HH, Kono T (2003). "Nevus of Ota: clinical aspects and management". Skinmed 2 (2): 89–96; quiz 97–8. doi:10.1111/j.1540-9740.2003.01706.x. PMID 14673306. http://www.lejacq.com/articleDetail.cfm?pid=SKINmed_2;2:89.
- ^ "eMedicine - Nevi of Ota and Ito : Article by Harvey Lui". http://www.emedicine.com/DERM/topic290.htm. Retrieved 2008-03-22.
- ^ Geronemus R. "Q-switched ruby laser therapy of nevus of Ota". Arch Dermatol. 128:1618-1622. 1992 [1]
- ^ Watanabe S, Takahashi H (1994). "Treatment of nevus of Ota with the Q-switched ruby laser". N. Engl. J. Med. 331 (26): 1745–50. doi:10.1056/NEJM199412293312604. PMID 7984195. http://content.nejm.org/cgi/pmidlookup?view=short&pmid=7984195&promo=ONFLNS19.
Gonadal tumors, paraganglioma, and glomus (ICD-O 8590-8719) Gonadal/
sex cord-gonadal stromal (8590-8679)sex cord (Granulosa cell tumour, Sertoli cell tumor)
stroma (Thecoma, Leydig cell tumor)
both (Sertoli-Leydig cell tumour, Luteoma)Paragangliomas And
Glomus tumors (8680-8719)Neuroendocrine tumor: Paraganglioma (Pheochromocytoma)
Vascular tissue neoplasm: Glomus tumor (Glomangiosarcoma)M: NEO
tsoc, mrkr
tumr, epon, para
drug (L1i/1e/V03)
Tumors: Skin neoplasm, Nevi and melanomas (C43/D22, 172/216, ICD-O 8720-8799) Melanoma Mucosal melanoma · Superficial spreading melanoma · Nodular melanoma · lentigo (Lentigo maligna/Lentigo maligna melanoma, Acral lentiginous melanoma)Amelanotic melanoma · Desmoplastic melanoma · Melanoma with features of a Spitz nevus · Melanoma with small nevus-like cells · Polypoid melanoma · Soft-tissue melanomaNevus/
melanocytic nevusNevus of Ito/Nevus of Ota · Compound nevus · Spitz nevus (Pigmented spindle cell nevus) · Halo nevus · Pseudomelanoma
Blue nevus (Blue nevus of Jadassohn–Tièche, Cellular blue nevus, Epithelioid blue nevus, Deep penetrating nevus, Amelanotic blue nevus, Malignant blue nevus)
Congenital melanocytic nevus (Giant pigmented nevus, Medium-sized congenital nevocytic nevus, Small-sized congenital nevocytic nevus)
Balloon cell nevus · Dysplastic nevus/Dysplastic nevus syndrome
Categories:- Melanocytic nevi and neoplasms
Wikimedia Foundation. 2010.