Lentigo maligna melanoma

Lentigo maligna melanoma

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB = 32059
ICD10 =
ICD9 =
ICDO = 8742
OMIM =
MedlinePlus =
eMedicineSubj = med
eMedicineTopic = 1278
MeshID = D018327

Lentigo maligna is a melanoma "in situ" that consists of malignant cells but does not show invasive growth. It typically progresses very slowly and can remain in a non-invasive form for years. The transition to true melanoma is marked by the appearance of a bumpy surface (itself a marker of vertical growth and invasion), at which point it is called lentigo maligna melanoma. It is normally found in the elderly (peak incidence in the 9th decade), on skin areas with high levels of sun exposure like the face and forearms.

Treatment

Therapy of lentigo maligna consists of surgical excision (the best and most common solution) or radiotherapy (only in special cases). Topical treatment with imiquimod cream has recently been used as an experimental treatment.

Presentation

Characteristics include a blue/black stain of skin initially. Skin is thin, about 4-5 cell layers thick, which is often related to aging. Histological features include epidermal atrophy and increased number of melanocytes.


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • lentigo maligna melanoma — a cutaneous malignant melanoma found most often on sun exposed areas of the skin, especially the face. It begins as a circumscribed macular patch of mottled pigmentation, showing shades of dark brown, tan, or black (lentigo maligna or melanotic… …   Medical dictionary

  • lentigo maligna — lentigo ma·lig·na mə lig nə n a precancerous lesion on the skin esp. in areas exposed to the sun (as the face) that is flat, mottled, and brownish with an irregular outline and grows slowly over a period of years * * * a type of lentigo that… …   Medical dictionary

  • Lentigo maligna — Die Frankfurterin Josepha Gobin, 71 Jahre alt. Trotz einer unübersehbaren Lentigo maligna an der Stirn lebte sie noch 15 Jahre weiter Als Lentigo maligna (Synonyme: Melanoma in situ, melanotische Präkanzerose, Melanosis circumscripta… …   Deutsch Wikipedia

  • Melanoma — Classification and external resources A melanoma ICD 10 C43 …   Wikipedia

  • Lentigo — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 34325 ICD10 = ICD10|L|81|4|l|80 ICD9 = ICD9|709.09 ICDO = OMIM = MedlinePlus = eMedicineSubj = derm eMedicineTopic = 221 MeshID = D007911 Lentigo is a type of brown skin lesion with high… …   Wikipedia

  • melanoma — m. oncol. Tumor maligno derivado de los melanocitos que se desarrolla en cualquier zona de la piel, aunque con más frecuencia en brazos, piernas, cara y órganos genitales. Se manifiesta como una zona de contorno más o menos irregular, un poco… …   Diccionario médico

  • Lentigo juvenilis — Klassifikation nach ICD 10 L81.4 Lentigo …   Deutsch Wikipedia

  • Lentigo senilis — Klassifikation nach ICD 10 L81.4 Lentigo …   Deutsch Wikipedia

  • Lentigo simplex — Klassifikation nach ICD 10 L81.4 Lentigo …   Deutsch Wikipedia

  • Lentigo solaris — Klassifikation nach ICD 10 L81.4 Lentigo …   Deutsch Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”