Bacterial outer membrane

Bacterial outer membrane
Structure of gram-negative cell envelope

The bacterial outer membrane is found in Gram-negative bacteria. Its composition is distinct from that of the cytoplasmic membrane - among other things, the outer leaflet of the membrane includes a complex lipopolysaccharide whose lipid portion acts as an endotoxin - and it is linked to the cell's peptidoglycan by Braun's lipoprotein.

Porins can be found in this layer.[1]

Clinical significance

If lipid A, part of the LPS, enters the circulatory system it causes a toxic reaction by activating TLR 4. Lipid A is very immunogenic and causes an aggressive response by the immune system. The sufferer will have a high temperature and respiration rate and a low blood pressure. This may lead to endotoxic shock, which may be fatal.

See also

References

  1. ^ van der Ley P, Heckels JE, Virji M, Hoogerhout P, Poolman JT (September 1991). "Topology of outer membrane porins in pathogenic Neisseria spp". Infection and immunity 59 (9): 2963–71. PMC 258120. PMID 1652557. http://iai.asm.org/cgi/pmidlookup?view=long&pmid=1652557. 
v · Microbiology: Bacteria
Pathogenic bacteria

Bacterial disease · Coley's Toxins · Exotoxin · Lysogenic cycle
Human flora
Substrate preference
Oxygen preference
Structures
Outside envelope
Bacterial capsule · Slime layer · S-layer · Glycocalyx
Pilus · Fimbria
Composite
Shapes
Bacterial cellular morphologies · L-form bacteria · Coccus (Diplococcus)  · Bacillus · Coccobacillus

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)

Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Outer membrane — can refer to: Bacterial outer membrane Outer mitochondrial membrane The outer membrane of the chloroplast This disambiguation page lists articles associated with the same title. If an …   Wikipedia

  • Outer membrane phospholipase A1 — Phospholipase A1 Identifiers Symbol PLA1 Pfam PF02253 …   Wikipedia

  • Outer membrane efflux proteins — Outer membrane efflux protein Identifiers Symbol OEP Pfam PF02321 …   Wikipedia

  • Outer membrane protein W family — Outer membrane protein W Identifiers Symbol OmpW Pfam …   Wikipedia

  • Virulence-related outer membrane protein family — Virulence related OMP Identifiers Symbol Ail Lom Pfam PF06316 …   Wikipedia

  • Bacterial phyla — …   Wikipedia

  • Outer mitochondrial membrane — Mitochondria structure : 1) Inner membrane 2) Outer membrane 3) Crista 4) Matrix The outer mitochondrial membrane, which encloses the entire organelle, has a protein to phospholipid ratio similar to the eukaryotic plasma membrane (about 1:1… …   Wikipedia

  • Bacterial cell structure — Bacteria, despite their apparent simplicity, contain a well developed cell structure which is responsible for many of their unique biological properties. Many structural features are unique to bacteria and are not found among archaea or… …   Wikipedia

  • General bacterial porin family — Pfam box Symbol = Porin 1 Name = Gram negative porin width =250 caption = Pfam= PF00267 InterPro= IPR001702 SMART= PROSITE = PDOC00498 SCOP = 1mpf TCDB = 1.B.1 OPM family= 31 OPM protein= 1pho PDB=PDB3|2fgrA:21 351 PDB3|2fgqX:20 351PDB3|1pho :27… …   Wikipedia

  • Inner membrane — The inner membrane is the biological membrane (phospholipid bilayer) of an organelle or Gram negative bacteria that is within an outer membrane. In eukaryotic cells, this inner membrane is present within the nuclear envelope, mitochondria and… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”