Major histocompatibility complex, class I-related

"MR1" redirects here. For the first game in the Monster Rancher series, see Monster Rancher (video game).

Major histocompatibility complex, class I-related
Identifiers
Symbols	MR1; FLJ31593; HLALS
External IDs	OMIM: 600764 MGI: 1195463 HomoloGene: 123981 GeneCards: MR1 Gene
Gene Ontology Molecular function • MHC class I receptor activity Cellular component • extracellular region • endoplasmic reticulum • plasma membrane • integral to membrane • MHC class I protein complex Biological process • antigen processing and presentation of peptide antigen via MHC class I • immune response • antigen processing and presentation Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3140	15064
Ensembl	ENSG00000153029	ENSMUSG00000026471
UniProt	Q95460	n/a
RefSeq (mRNA)	NM_001194999.1	NM_008209.4
RefSeq (protein)	NP_001181928.1	NP_032235.1
Location (UCSC)	Chr 1: 181 – 181.03 Mb	Chr 1: 156.98 – 156.99 Mb
PubMed search	[1]	[2]

Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene.^[1][2][3]

References

1. ^ Hashimoto K, Hirai M, Kurosawa Y (Aug 1995). "A gene outside the human MHC related to classical HLA class I genes". Science 269 (5224): 693–5. doi:10.1126/science.7624800. PMID 7624800. 
2. ^ Yamaguchi H, Kurosawa Y, Hashimoto K (Nov 1998). "Expanded genomic organization of conserved mammalian MHC class I-related genes, human MR1 and its murine ortholog". Biochem Biophys Res Commun 250 (3): 558–64. doi:10.1006/bbrc.1998.9353. PMID 9784382. 
3. ^ "Entrez Gene: MR1 major histocompatibility complex, class I-related". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3140. 

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. 
• Yamaguchi H, Hirai M, Kurosawa Y, Hashimoto K (1997). "A highly conserved major histocompatibility complex class I-related gene in mammals.". Biochem. Biophys. Res. Commun. 238 (3): 697–702. doi:10.1006/bbrc.1997.7379. PMID 9325151. 
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. 
• Riegert P, Wanner V, Bahram S (1998). "Genomics, isoforms, expression, and phylogeny of the MHC class I-related MR1 gene.". J. Immunol. 161 (8): 4066–77. PMID 9780177. 
• Parra-Cuadrado JF, Navarro P, Mirones I, et al. (2001). "A study on the polymorphism of human MHC class I-related MR1 gene and identification of an MR1-like pseudogene.". Tissue Antigens 56 (2): 170–2. doi:10.1034/j.1399-0039.2000.560211.x. PMID 11019920. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Miley MJ, Truscott SM, Yu YY, et al. (2003). "Biochemical features of the MHC-related protein 1 consistent with an immunological function.". J. Immunol. 170 (12): 6090–8. PMID 12794138. 
• Hempelmann A, Kumar S, Muralitharan S, Sander T (2007). "Myofibrillogenesis regulator 1 gene (MR-1) mutation in an Omani family with paroxysmal nonkinesigenic dyskinesia.". Neurosci. Lett. 402 (1-2): 118–20. doi:10.1016/j.neulet.2006.03.048. PMID 16632198.