Damnacanthal

Damnacanthal
Damnacanthal
Chemical structure of damnacanthal
Identifiers
CAS number 477-84-9 N
PubChem 2948
ChemSpider 2843 YesY
ChEMBL CHEMBL212948 YesY
Jmol-3D images Image 1
Properties
Molecular formula C16H10O5
Molar mass 282.25 g mol−1
Exact mass 282.052823 u
Related compounds
Related arylformaldehydes Gossypol

Pyridoxal

 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Damnacanthal is an anthraquinone which acts as a p56lck tyrosine kinase inhibitor.[1] It can be extracted from Morinda citrifolia.[2]

References

  1. ^ Faltynek CR, Schroeder J, Mauvais P, et al. (September 1995). "Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity". Biochemistry 34 (38): 12404–10. doi:10.1021/bi00038a038. PMID 7547985. 
  2. ^ Anekpankul T, Goto M, Sasaki M, et al. (July 2007). "Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water". Separation and Purification Technology 55 (3): 343–349. doi:10.1016/j.seppur.2007.01.004.