- Damnacanthal
-
Damnacanthal 3-Hydroxy-1-methoxy-9,10-dioxoanthracene-2-carbaldehydeOther names3-Hydroxy-1-methoxyanthraquinone-2-aldehydeIdentifiers CAS number 477-84-9 PubChem 2948 ChemSpider 2843 ChEMBL CHEMBL212948 Jmol-3D images Image 1 - COC1=C2C(=CC(=C1C=O)O)C(=O)C3=CC=CC=C3C2=O
Properties Molecular formula C16H10O5 Molar mass 282.25 g mol−1 Exact mass 282.052823 u Related compounds Related arylformaldehydes Gossypol
(verify) (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references Damnacanthal is an anthraquinone which acts as a p56lck tyrosine kinase inhibitor.[1] It can be extracted from Morinda citrifolia.[2]
References
- ^ Faltynek CR, Schroeder J, Mauvais P, et al. (September 1995). "Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity". Biochemistry 34 (38): 12404–10. doi:10.1021/bi00038a038. PMID 7547985.
- ^ Anekpankul T, Goto M, Sasaki M, et al. (July 2007). "Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water". Separation and Purification Technology 55 (3): 343–349. doi:10.1016/j.seppur.2007.01.004.
Hydroxyanthraquinones |Dihydroxyanthraquinones Alizarin | Aloe emodin | Damnacanthal | 1,3-Dihydroxyanthraquinone | 1,4-Dihydroxyanthraquinone | 1,8-Dihydroxyanthraquinone | RheinTrihydroxyanthraquinones Tetrahydroxyanthraquinones 1,2,4-Trihydroxyanthraquinone | 1,3,8-TrihydroxyanthraquinonePentahydroxyanthraquinones |Hexahydroxyanthraquinones |Heptahydroxyanthraquinones |Misc: Anthraquinone drugs | Anthraquinone dyes Carminic acid | 2-Ethylanthraquinone | Quinalizarin | Rufigallol | Senna glycosides | Sodium 2-anthraquinonesulfonateThis antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it. This article about a natural phenol is a stub. You can help Wikipedia by expanding it.