Rhein (molecule)

Rhein (molecule)
Chemical structure of rhein
CAS number 478-43-3 YesY=
PubChem 10168
Jmol-3D images Image 1
Molecular formula C15H8O6
Molar mass 284.22 g/mol
Exact mass 284.032088 u
Appearance Orange crystals[1]
Melting point

350-352 °C[1]

Solubility in water Insoluble in water
EU classification Xi
R-phrases R36/R37/R38
S-phrases S26-37/S39
Main hazards Irritant
 N (molecule) (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Rhein, also known as cassic acid, is a substance in the anthraquinone group found in rhubarb species like Rheum undulatum[2] or Rheum palmatum[1] or in Cassia reticulata.[3] Rhein has been reevaluated as a new antibacterial agent against Staphylococcus aureus in 2008.[4]

See also


  1. ^ a b c Cassic acid on www.naturestandard.com
  2. ^ Pharmacokinetic analysis of rhein in Rheum undulatum L. Je-Hyun Lee, Jong Moon Kim and Chungsook Kim, Journal of Ethnopharmacology, Volume 84, Issue 1, January 2003, Pages 5-9, doi:10.1016/S0378-8741(02)00222-2
  3. ^ Identification of the antibiotic substance from Cassia reticulata as 4,5-Dihydroxyanthraquinone-2-carboxylic acid. Marjorie Anchel, 1948
  4. ^ Global transcriptional response of Staphylococcus aureus to Rhein, a Natural Plant Product. Lu Yu, Hua Xiang, Junwen Fan, Dacheng Wang, Feng Yang, Na Guo, Qi Jin and Xuming Deng, Journal of Biotechnology, Volume 135, Issue 3, 30 June 2008, Pages 304-308, doi:10.1016/j.jbiotec.2008.04.010