Codoxime

Codoxime

Systematic (IUPAC) name
(((4,5α- Epoxy- 3-methoxy- 17-methylmorphinan- 6-ylidene) amino)oxy) acetic acid
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	7125-76-0
ATC code	None
PubChem	CID 9570253
ChemSpider	7844721
UNII	JT5I2F57F7 Y
KEGG	D03581
Synonyms	Codoxime
Chemical data
Formula	C20H24N2O5
Mol. mass	372.415 g/mol
SMILES	eMolecules & PubChem

Codoxime (Codossima) is an opiate analogue that is a derivative of hydrocodone, where the 6-ketone group has been replaced by carboxymethyloxime. It has primarily antitussive effects^[1] and was found to have moderate potential to cause dependence in animal studies.^[2]

References

1. ^ Jack Fishman. Morphinone and Codeinone Derivatives. US Patent 3153042
2. ^ Jasinski DR, Martin WR. Assessment of the dependence-producing properties of dihydrocodeinone and codoxime. Clinical Pharmacology and Therapeutics. 1967 Mar-Apr;8(2):266-70. PMID 6021586

This analgesic-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Antitussives Morphinans Phenol ethers Mu-opioid agonists Semisynthetic opioids Analgesic stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем сделать НИР Leave It to Beaver characters Hanriot HD.17 Look at other dictionaries: Opioid — Endogenous opioid peptides Skeletal molecular images Adrenorphin Amidorphin Casomorphin …   Wikipedia Codeine — For other uses, see Codeine (disambiguation). Codeine Systematic (IUPAC) name (5α,6α) 7,8 didehydro 4,5 epoxy 3 methoxy 17 methylmorphinan 6 ol Cli …   Wikipedia Morphine — This article is about the drug. For other meanings, see Morphine (disambiguation). Morphia redirects here. For other uses, see Morphia (disambiguation). Not to be confused with Morphinae, Morphea, or Morpholine. Morphine …   Wikipedia Opiate — For other uses see Opiate (disambiguation), or for the class of drugs see Opioid. Harvesting the poppy pod. In medicine, the term opiate describes any of the narcotic opioid alkaloids found as natural products in the opium poppy plant …   Wikipedia Phencyclidine — Systematic (IUPAC) name …   Wikipedia Loperamide — Imodium redirects here. For the song by Nirvana, see Breed (song). Loperamide Systematic (IUPAC) name …   Wikipedia Pethidine — Systematic (IUPAC) name …   Wikipedia Opioid receptor — Opioid receptors are a group of G protein coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are 40% identical to somatostatin… …   Wikipedia Oxymorphone — Systematic (IUPAC) name 4,5α epoxy 3,14 dihydroxy 17 methylmorphinan 6 one Clinical data Trade names …   Wikipedia Sufentanil — Systematic (IUPAC) name N [4 (methoxymethyl) …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”