Nuclear mitotic apparatus protein 1

Nuclear mitotic apparatus protein 1
Nuclear mitotic apparatus protein 1
Identifiers
Symbols NUMA1; NUMA
External IDs OMIM164009 MGI2443665 HomoloGene38150 GeneCards: NUMA1 Gene
RNA expression pattern
PBB GE NUMA1 200747 s at tn.png
PBB GE NUMA1 214251 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4926 101706
Ensembl ENSG00000137497 ENSMUSG00000066306
UniProt Q14980 n/a
RefSeq (mRNA) NM_006185 NM_133947.3
RefSeq (protein) NP_006176 NP_598708.3
Location (UCSC) Chr 11:
71.71 – 71.79 Mb
Chr 7:
109.08 – 109.16 Mb
PubMed search [1] [2]

Nuclear mitotic apparatus protein 1 is a protein that in humans is encoded by the NUMA1 gene.[1][2]


Interactions

Nuclear mitotic apparatus protein 1 has been shown to interact with PIM1,[3] Band 4.1,[4] GPSM2[5] and EPB41L1.[6]

References

  1. ^ Sparks CA, Bangs PL, McNeil GP, Lawrence JB, Fey EG (Oct 1993). "Assignment of the nuclear mitotic apparatus protein NuMA gene to human chromosome 11q13". Genomics 17 (1): 222–224. doi:10.1006/geno.1993.1307. PMID 8406455. 
  2. ^ "Entrez Gene: NUMA1 nuclear mitotic apparatus protein 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4926. 
  3. ^ Bhattacharya, Nandini; Wang Zeping, Davitt Christine, McKenzie Ian F C, Xing Pei-Xiang, Magnuson Nancy S (Jul. 2002). "Pim-1 associates with protein complexes necessary for mitosis". Chromosoma (Germany) 111 (2): 80–95. doi:10.1007/s00412-002-0192-6. ISSN 0009-5915. PMID 12111331. 
  4. ^ Mattagajasingh, S N; Huang S C, Hartenstein J S, Snyder M, Marchesi V T, Benz E J (Apr. 1999). "A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein". J. Cell Biol. (UNITED STATES) 145 (1): 29–43. doi:10.1083/jcb.145.1.29. ISSN 0021-9525. PMC 2148212. PMID 10189366. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2148212. 
  5. ^ Du, Q; Stukenberg P T, Macara I G (Dec. 2001). "A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization". Nat. Cell Biol. (England) 3 (12): 1069–1075. doi:10.1038/ncb1201-1069. ISSN 1465-7392. PMID 11781568. 
  6. ^ Ye, K; Compton D A, Lai M M, Walensky L D, Snyder S H (Dec. 1999). "Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor". J. Neurosci. (UNITED STATES) 19 (24): 10747–56. PMID 10594058. 

Further reading


Wikimedia Foundation. 2010.

Нужно написать реферат?

Look at other dictionaries:

  • Spindle apparatus — This article is about the cellular structure. For other uses, see Spindle (disambiguation). Micrograph showing condensed chromosomes in blue and the mitotic spindle in green during prometaphase of mitosis In cell biology, the spindle fibers are… …   Wikipedia

  • EPB41L1 — Erythrocyte membrane protein band 4.1 like 1, also known as EPB41L1, is a human gene.cite web | title = Entrez Gene: EPB41L1 erythrocyte membrane protein band 4.1 like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Poly ADP ribose polymerase — For the sound, see Parp (onomatopoeic). ADP ribose …   Wikipedia

  • angiosperm — /an jee euh sperrm /, n. Bot. a plant having its seeds enclosed in an ovary; a flowering plant. Cf. gymnosperm. [ANGIO + SPERM] * * * ▪ plant Introduction       any member of the more than 300,000 species of flowering plants (division Anthophyta) …   Universalium

  • LATS1 — LATS, large tumor suppressor, homolog 1 (Drosophila), also known as LATS1, is a human gene.cite web | title = Entrez Gene: LATS1 LATS, large tumor suppressor, homolog 1 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • Cleavage (embryo) — In embryology, cleavage is the division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived …   Wikipedia

  • List of genetics-related topics — This is a list of terms related to genetics. NOTOC # * 3 end * 5 end A * Acentric chromosome * Achondroplasia * Active site * Adam s Curse * Adaptation * Adenine * Adenosine * Adenovirus * Adenosine diphosphate (ADP) * Ala * Alagille syndrome *… …   Wikipedia

  • List of genetic engineering topics — NOTOC # 3 end 5 end A Acentric chromosome Achondroplasia Active site Adam s Curse Adaptation Adenine Adenosine Adenosine diphosphate Adenovirus ADP Ala Alagille syndrome Albino Alcoholism Alkylating agent Allele Allele frequency Alleles… …   Wikipedia

  • Zyxin — Zyxin, also known as ZYX, is a human gene.cite web | title = Entrez Gene: ZYX zyxin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=7791| accessdate = ] PBB Summary section title = summary text = Focal… …   Wikipedia

  • NUMA — Non Uniform Memory Access (Computing » General) * National Underwater And Marine Agency (Governmental » US Government) * Nonuniform Memory Access (Computing » Drivers) * Nuclear protein that associated with the Mitotic Apparatus (Medical »… …   Abbreviations dictionary

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”