Nuclear mitotic apparatus protein 1

Nuclear mitotic apparatus protein 1
Nuclear mitotic apparatus protein 1
Identifiers
Symbols NUMA1; NUMA
External IDs OMIM164009 MGI2443665 HomoloGene38150 GeneCards: NUMA1 Gene
RNA expression pattern
PBB GE NUMA1 200747 s at tn.png
PBB GE NUMA1 214251 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4926 101706
Ensembl ENSG00000137497 ENSMUSG00000066306
UniProt Q14980 n/a
RefSeq (mRNA) NM_006185 NM_133947.3
RefSeq (protein) NP_006176 NP_598708.3
Location (UCSC) Chr 11:
71.71 – 71.79 Mb
Chr 7:
109.08 – 109.16 Mb
PubMed search [1] [2]

Nuclear mitotic apparatus protein 1 is a protein that in humans is encoded by the NUMA1 gene.[1][2]


Interactions

Nuclear mitotic apparatus protein 1 has been shown to interact with PIM1,[3] Band 4.1,[4] GPSM2[5] and EPB41L1.[6]

References

  1. ^ Sparks CA, Bangs PL, McNeil GP, Lawrence JB, Fey EG (Oct 1993). "Assignment of the nuclear mitotic apparatus protein NuMA gene to human chromosome 11q13". Genomics 17 (1): 222–224. doi:10.1006/geno.1993.1307. PMID 8406455. 
  2. ^ "Entrez Gene: NUMA1 nuclear mitotic apparatus protein 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4926. 
  3. ^ Bhattacharya, Nandini; Wang Zeping, Davitt Christine, McKenzie Ian F C, Xing Pei-Xiang, Magnuson Nancy S (Jul. 2002). "Pim-1 associates with protein complexes necessary for mitosis". Chromosoma (Germany) 111 (2): 80–95. doi:10.1007/s00412-002-0192-6. ISSN 0009-5915. PMID 12111331. 
  4. ^ Mattagajasingh, S N; Huang S C, Hartenstein J S, Snyder M, Marchesi V T, Benz E J (Apr. 1999). "A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein". J. Cell Biol. (UNITED STATES) 145 (1): 29–43. doi:10.1083/jcb.145.1.29. ISSN 0021-9525. PMC 2148212. PMID 10189366. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2148212. 
  5. ^ Du, Q; Stukenberg P T, Macara I G (Dec. 2001). "A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization". Nat. Cell Biol. (England) 3 (12): 1069–1075. doi:10.1038/ncb1201-1069. ISSN 1465-7392. PMID 11781568. 
  6. ^ Ye, K; Compton D A, Lai M M, Walensky L D, Snyder S H (Dec. 1999). "Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor". J. Neurosci. (UNITED STATES) 19 (24): 10747–56. PMID 10594058. 

Further reading


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