GPSM2

G-protein signalling modulator 2 (AGS3-like, C. elegans), also known as GPSM2, is a human gene.cite web | title = Entrez Gene: GPSM2 G-protein signalling modulator 2 (AGS3-like, C. elegans)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29899| accessdate = ]

PBB_Summary
section_title =
summary_text = Heterotrimeric G proteins transduce extracellular signals received by cell surface receptors into integrated cellular responses. GPSM2 belongs to a group of proteins that modulate activation of G proteins (Blumer et al., 2002). [supplied by OMIM] cite web | title = Entrez Gene: GPSM2 G-protein signalling modulator 2 (AGS3-like, C. elegans)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29899| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Mochizuki N, Cho G, Wen B, Insel PA |title=Identification and cDNA cloning of a novel human mosaic protein, LGN, based on interaction with G alpha i2. |journal=Gene |volume=181 |issue= 1-2 |pages= 39–43 |year= 1997 |pmid= 8973305 |doi=
*cite journal | author=Du Q, Stukenberg PT, Macara IG |title=A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. |journal=Nat. Cell Biol. |volume=3 |issue= 12 |pages= 1069–75 |year= 2002 |pmid= 11781568 |doi= 10.1038/ncb1201-1069
*cite journal | author=Blumer JB, Chandler LJ, Lanier SM |title=Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis. |journal=J. Biol. Chem. |volume=277 |issue= 18 |pages= 15897–903 |year= 2002 |pmid= 11832491 |doi= 10.1074/jbc.M112185200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Marty C, Browning DD, Ye RD |title=Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras. |journal=Mol. Cell. Biol. |volume=23 |issue= 11 |pages= 3847–58 |year= 2003 |pmid= 12748287 |doi=
*cite journal | author=Kaushik R, Yu F, Chia W, "et al." |title=Subcellular localization of LGN during mitosis: evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression. |journal=Mol. Biol. Cell |volume=14 |issue= 8 |pages= 3144–55 |year= 2004 |pmid= 12925752 |doi= 10.1091/mbc.E03-04-0212
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Du Q, Macara IG |title=Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. |journal=Cell |volume=119 |issue= 4 |pages= 503–16 |year= 2004 |pmid= 15537540 |doi= 10.1016/j.cell.2004.10.028
*cite journal | author=Yasumi M, Sakisaka T, Hoshino T, "et al." |title=Direct binding of Lgl2 to LGN during mitosis and its requirement for normal cell division. |journal=J. Biol. Chem. |volume=280 |issue= 8 |pages= 6761–5 |year= 2005 |pmid= 15632202 |doi= 10.1074/jbc.C400440200
*cite journal | author=Yang J, Kamide K, Kokubo Y, "et al." |title=Genetic variations of regulator of G-protein signaling 2 in hypertensive patients and in the general population. |journal=J. Hypertens. |volume=23 |issue= 8 |pages= 1497–505 |year= 2005 |pmid= 16003176 |doi=
*cite journal | author=Izaki T, Kamakura S, Kohjima M, Sumimoto H |title=Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3. |journal=Biochem. Biophys. Res. Commun. |volume=341 |issue= 4 |pages= 1001–6 |year= 2006 |pmid= 16458856 |doi= 10.1016/j.bbrc.2006.01.050

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