D-amino-acid N-acetyltransferase

D-amino-acid N-acetyltransferase
D-amino-acid N-acetyltransferase
Identifiers
EC number 2.3.1.36
CAS number 37257-15-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a D-amino-acid N-acetyltransferase (EC 2.3.1.36) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + a D-amino acid \rightleftharpoons CoA + an N-acetyl-D-amino acid

Thus, the two substrates of this enzyme are acetyl-CoA and D-amino acid, whereas its two products are CoA and N-acetyl-D-amino acid.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:D-amino-acid N-acetyltransferase. Other names in common use include D-amino acid acetyltransferase, and D-amino acid-alpha-N-acetyltransferase. This enzyme participates in phenylalanine metabolism.

References

  • Zenk MH and Schmitt J (1965). "Reinigung und Eigenschaften von Acetyl-CoA:D-Aminosaure-alpha-N-Acetyltransferase aus Hefe". Biochem. Z. 342: 54–65.