Peptide alpha-N-acetyltransferase
- Peptide alpha-N-acetyltransferase
In enzymology, a peptide alpha-N-acetyltransferase (EC number|2.3.1.88) is an enzyme that catalyzes the chemical reaction
:acetyl-CoA + peptide Nalpha-acetylpeptide + CoA
Thus, the two substrates of this enzyme are acetyl-CoA and peptide, whereas its two products are Nalpha-acetylpeptide and CoA.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:peptide Nalpha-acetyltransferase. Other names in common use include beta-endorphin acetyltransferase, peptide acetyltransferase, protein N-terminal acetyltransferase, NAT, Nalpha-acetyltransferase, amino-terminal amino acid-acetylating enzyme, and acetyl-CoA:peptide alpha-N-acetyltransferase.
tructural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|2OB0 and PDB link|2PSW.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|83452-29-3."
Gene Ontology (GO) codes
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