- Citrate CoA-transferase
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citrate CoA-transferase Identifiers EC number 2.8.3.10 CAS number 65187-14-6 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a citrate CoA-transferase (EC 2.8.3.10) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + citrate acetate + (3S)-citryl-CoA
Thus, the two substrates of this enzyme are acetyl-CoA and citrate, whereas its two products are acetate and (3S)-citryl-CoA.
This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:citrate CoA-transferase. This enzyme participates in citrate cycle (tca cycle).
References
- Dimroth P, Loyal R, Eggerer H (1977). "Characterization of the isolated transferase subunit of citrate lyase as a CoA-Transferase. Evidence against a covalent enzyme-substrate intermediate". Eur. J. Biochem. 80 (2): 479–88. doi:10.1111/j.1432-1033.1977.tb11903.x. PMID 336371.
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