Dimenoxadol

Dimenoxadol

Systematic (IUPAC) name
2-(dimethylamino)ethyl 2-ethoxy-2,2-diphenylacetate
Clinical data
Pregnancy cat.	?
Legal status	Schedule I (US)
Identifiers
CAS number	509-78-4 Y
ATC code	None
PubChem	CID 17036
DrugBank	DB01461
ChemSpider	16137 Y
UNII	4D65PBX0VK Y
Synonyms	Dimenoxadol, Estocin
Chemical data
Formula	C20H25NO3
Mol. mass	327.42 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C20H25NO3/c1-4-24-20(17-11-7-5-8-12-17,18-13-9-6-10-14-18)19(22)23-16-15-21(2)3/h5-14H,4,15-16H2,1-3H3 Y Key:RHUWRJWFHUKVED-UHFFFAOYSA-N Y
Y(what is this?)  (verify)

Dimenoxadol (Estocin) is an opioid analgesic which is a diphenylacetic acid derivative, related to other drugs such as dextropropoxyphene.

It was invented in Germany in the 1950s^[1], and produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.^[2][3][4]

References

1. ^ GB 716700, Boehringer, A et al., "A new and improved analgesic and process for its production", published 10/13/1954 
2. ^ Gorbatova, E. N. (1967). "The pharmacology of estocin, an new analgesic". Stomatologiia 46 (2): 22–25. PMID 5232927.  edit
3. ^ Kingisepp, G. A.; Kurvits, K.; Nurmand, L. B. (1969). "Pharmacology of dimethylaminoethyl ester of diphenylethoxyacetic acid hydrochloride--estocin". Farmakologiia i toksikologiia 32 (6): 710–712. PMID 5381602.  edit
4. ^ Liberman, S. S. (1968). "Analgesic action of estocin (dimethylaminoethyl ester hydrochloride of alpha, alpha-diphenylethoxyacetic acid)". Farmakologiia i toksikologiia 31 (6): 668–671. PMID 5729519.  edit

This analgesic-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Synthetic opioids Ethers Carboxylate esters Mu-opioid agonists Analgesic stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем написать реферат Reflectopallium pseudophyllum 42nd Street (disambiguation) Look at other dictionaries: dimenoxadol — noun A particular narcotic painkiller …   Wiktionary Дименоксадол — (Эстоцин, Aesthocinum). Диметиламиниоэтилового эфира дифенил этоксиуксусной кислоты гидрохлорид. Синонимы: Dimenoxadoll hydrochloridum, Dimenoxadol hydrochloride, Estocin, Lokarin, Propalgyl. Входит в переч …   Википедия Opioid — Endogenous opioid peptides Skeletal molecular images Adrenorphin Amidorphin Casomorphin …   Wikipedia Morphine — This article is about the drug. For other meanings, see Morphine (disambiguation). Morphia redirects here. For other uses, see Morphia (disambiguation). Not to be confused with Morphinae, Morphea, or Morpholine. Morphine …   Wikipedia Opiate — For other uses see Opiate (disambiguation), or for the class of drugs see Opioid. Harvesting the poppy pod. In medicine, the term opiate describes any of the narcotic opioid alkaloids found as natural products in the opium poppy plant …   Wikipedia Phencyclidine — Systematic (IUPAC) name …   Wikipedia Loperamide — Imodium redirects here. For the song by Nirvana, see Breed (song). Loperamide Systematic (IUPAC) name …   Wikipedia Pethidine — Systematic (IUPAC) name …   Wikipedia Opioid receptor — Opioid receptors are a group of G protein coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are 40% identical to somatostatin… …   Wikipedia Oxymorphone — Systematic (IUPAC) name 4,5α epoxy 3,14 dihydroxy 17 methylmorphinan 6 one Clinical data Trade names …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”