- Bisdisulizole disodium
-
Bisdisulizole disodium 
disodium 2,2'-(1,4-phenylene)bis(6-sulfo-1H-benzimidazole-4-sulfonate)Identifiers CAS number 180898-37-7 PubChem 11158166 ChemSpider 9333274 
Jmol-3D images Image 1 - [Na+].[Na+].O=S(=O)(O)c1cc2nc(nc2c(c1)S([O-])(=O)=O)c5ccc(c4nc3c(cc(cc3n4)S(=O)(=O)O)S([O-])(=O)=O)cc5
- InChI=1S/C20H14N4O12S4.2Na/c25-37(26,27)11-5-13-17(15(7-11)39(31,32)33)23-19(21-13)9-1-2-10(4-3-9)20-22-14-6-12(38(28,29)30)8-16(18(14)24-20)40(34,35)36;;/h1-8H,(H,21,23)(H,22,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36);;/q;2*+1/p-2
Key: GLCJMPWWQKKJQZ-UHFFFAOYSA-L
InChI=1/C20H14N4O12S4.2Na/c25-37(26,27)11-5-13-17(15(7-11)39(31,32)33)23-19(21-13)9-1-2-10(4-3-9)20-22-14-6-12(38(28,29)30)8-16(18(14)24-20)40(34,35)36;;/h1-8H,(H,21,23)(H,22,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36);;/q;2*+1/p-2
Key: GLCJMPWWQKKJQZ-NUQVWONBAQ
Properties Molecular formula C20H12N4Na2O12S4 Molar mass 674.57 g mol−1 
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references Bisdisulizole disodium (INN[1]/USAN[2], trade name Neo Heliopan AP, INCI disodium phenyl dibenzimidazole tetrasulfonate) is a water soluble organic compound which is added to sunscreens to absorb UVA rays. It is marketed by Symrise.
Bisdisulizole disodium is not approved in the United States by the FDA, but it has been approved in the European Union since the year 2000[3] and other parts of the world.[4][5]
References
- ^ http://ec.europa.eu/enterprise/cosmetics/cosing/index.cfm?fuseaction=search.detailsPDF&id=75792
- ^ "Statement on a nonproprietary name adopted by the USAN Council: Bisdisulizole disodium". American Medical Association. April 4, 2006. http://www.ama-assn.org/ama1/pub/upload/mm/365/bisdiulizole_disodiu.pdf. Retrieved 2008-01-08.
- ^ Osstervalder U, Luther H, Herzog B (2001). "Über den Lichtschutzfaktor hinaus - neue effiziente und photostabile UVA-Filter" (in German). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 44 (5): 463–70. doi:10.1007/s001030170019.
- ^ "10. Sunscreens". Australian regulatory guidelines for OTC medicines. Commonwealth Department of Health and Ageing, Therapeutic Goods Administration. July 1, 2003. pp. p. 14. http://www.tga.gov.au/docs/pdf/argom_10.pdf. Retrieved 2008-01-08.
- ^ "Symrise UV protection products". Symrise. http://www.symrise.com/fileadmin/user_upload/pdf/Symrise_UV_protection_products.pdf. Retrieved 2008-08-10.
Sunscreening agents approved by the US FDA or other agencies UVA: 400–315 nm • UVB: 315–290 nm • chemical agents unless otherwise notedUVA filters Avobenzone (Parsol 1789) • Bisdisulizole disodium (Neo Heliopan AP) • Diethylamino hydroxybenzoyl hexyl benzoate (Uvinul A Plus) • Ecamsule (Mexoryl SX) • Methyl anthranilateUVB filters 4-Aminobenzoic acid (PABA) • Cinoxate • Ethylhexyl triazone (Uvinul T 150) • Homosalate • 4-Methylbenzylidene camphor (Parsol 5000) • Octyl methoxycinnamate (Octinoxate) • Octyl salicylate (Octisalate) • Padimate O (Escalol 507) • Phenylbenzimidazole sulfonic acid (Ensulizole) • Polysilicone-15 (Parsol SLX) • Trolamine salicylateUVA+UVB filters Bemotrizinol (Tinosorb S) • Benzophenones 1–12 • Dioxybenzone • Drometrizole trisiloxane (Mexoryl XL) • Iscotrizinol (Uvasorb HEB) • Octocrylene • Oxybenzone (Eusolex 4360) • Sulisobenzone • hybrid (chemical/physical): Bisoctrizole (Tinosorb M) • physical: Titanium dioxide, Zinc oxide
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