Overlap syndrome

Overlap syndrome
Overlap syndrome
Classification and external resources
ICD-10 M35.1

An overlap syndrome is an autoimmune disease of connective tissue[1] in which the patient presents with symptoms of two or more diseases. As much as 25% of all patients with connective tissue disease show signs of an overlap syndrome.

Examples of overlap syndromes include MCTD and scleromyositis, but the exact diagnosis depends from which diseases the patient shows symptoms. In overlap syndromes, features of systemic lupus erythematosus (SLE), systemic sclerosis, polymyositis, dermatomyositis, rheumatoid arthritis (RA) and Sjögren's syndrome are found often.[2]

References

  1. ^ "overlap syndrome" at Dorland's Medical Dictionary
  2. ^ Maddison PJ. (1991). "Overlap syndromes and mixed connective tissue disease". Curr Opin Rheumatol. 3 (6): 995–1000. doi:10.1097/00002281-199112000-00016. PMID 1772755. 
v · d · eSystemic CT disorders (M32–M36, 710)
General
Other hypersensitivity/autoimmune
Other

M: MUS, DF+DRCT

anat (h/n, u, t/d, a/p, l)/phys/devp/hist

noco(m, s, c)/cong(d)/tumr, sysi/epon, injr

proc, drug (M1A/3)

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