Small Cajal body specific RNA 8
- Small Cajal body specific RNA 8
Small Cajal body specific RNA 8 (also known as SCARNA8 or U92) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U2 spliceosomal RNA.
scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12[cite journal | last = Darzacq | first = X | coauthors = Jady BE, Verheggen C, Kiss AM, Bertrand E, Kiss T | year = 2002 | title = Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs | journal = EMBO J. | volume = 21 | pages = 2746–2756 | pmid = 12032087 | doi = 10.1093/emboj/21.11.2746] ]U92 belong to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure, conserved H/ACA-box motifs and is found associated with GAR1 [cite journal | author = Lestrade L, Weber MJ | title = snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs | journal = Nucleic Acids Res. | volume = 34 | issue = Database issue | pages = D158–62 | year = 2006 | pmid = 16381836 | doi = 10.1093/nar/gkj002 | issn = ] . ]References
External links
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* [http://www-snorna.biotoul.fr/plus.php?id=U92 snoRNABase entry for SCARNA8]
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Small Cajal body-specific RNA — Small Cajal body specific RNAs (scaRNAs) are a class of small nucleolar RNAs (snoRNAs) which specifically localise to the Cajal body, a nuclear organelle involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs or snurps). ScaRNAs… … Wikipedia
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Small Cajal body-specific RNA 18 — (also known as U91 or U4 8) is a type of small nuclear RNA which localises to the cajal bodies and proposed to guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12cite journal | author = Darzacq X, Jády … Wikipedia
Small Cajal body specific RNA 25 — (otherwise known as scaRNA25, HBI 100, MBI 100 and MBI 114) is a scaRNA which are a class of ncRNAs characterised as a small nuclear RNAs localised to the Cajal bodies [cite journal | last = Darzacq | first = X | coauthors = Jady BE, Verheggen C … Wikipedia
Small Cajal body specific RNA 13 — In molecular biology, Small Cajal body specific RNA 13 (also known as scaRNA13 or U93) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U2 and U5 spliceosomal RNA. scaRNAs are a specific class … Wikipedia
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