Small Cajal body-specific RNA 18
- Small Cajal body-specific RNA 18
small Cajal body-specific RNA 18 (also known as U91 or U4-8) is a type of small nuclear RNA which localises to the cajal bodies and proposed to guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12[cite journal | author = Darzacq X, Jády BE, Verheggen C, Kiss AM, Bertrand E, Kiss T | title = Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs | journal = EMBO J. | volume = 21 | issue = 11 | pages = 2746–56 | year = 2002 | pmid = 12032087 | doi = 10.1093/emboj/21.11.2746 | issn = ] . This snoRNA U91 appears to be belong to the C/D box class of snoRNAs][cite journal | author = Galardi S, Fatica A, Bachi A, Scaloni A, Presutti C, Bozzoni I | title = Purified box C/D snoRNPs are able to reproduce site-specific 2'-O-methylation of target RNA in vitro | journal = Mol. Cell. Biol. | volume = 22 | issue = 19 | pages = 6663–8 | year = 2002 | pmid = 12215523 | doi = | issn = ] . It was identified by Darzacq][cite journal | author = Lestrade L, Weber MJ | title = snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs | journal = Nucleic Acids Res. | volume = 34 | issue = Database issue | pages = D158–62 | year = 2006 | pmid = 16381836 | doi = 10.1093/nar/gkj002 | issn = ] . In humans the genomic location of U12-88/U4-8 is intergenic and the purified transcript has been shown to possess a methylated guanosine cap suggesting it is independently transcribed by RNA pol II ]References
External links
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* [http://www-snorna.biotoul.fr/plus.php?id=U91 snoRNABase entry for SCARNA18]
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Small Cajal body-specific RNA — Small Cajal body specific RNAs (scaRNAs) are a class of small nucleolar RNAs (snoRNAs) which specifically localise to the Cajal body, a nuclear organelle involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs or snurps). ScaRNAs… … Wikipedia
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Small Cajal body specific RNA 8 — (also known as SCARNA8 or U92) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U2 spliceosomal RNA.scaRNAs are a specific class of small nucleolar… … Wikipedia
Small Cajal body specific RNA 25 — (otherwise known as scaRNA25, HBI 100, MBI 100 and MBI 114) is a scaRNA which are a class of ncRNAs characterised as a small nuclear RNAs localised to the Cajal bodies [cite journal | last = Darzacq | first = X | coauthors = Jady BE, Verheggen C … Wikipedia
Small Cajal body specific RNA 13 — In molecular biology, Small Cajal body specific RNA 13 (also known as scaRNA13 or U93) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U2 and U5 spliceosomal RNA. scaRNAs are a specific class … Wikipedia
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