Small Cajal body specific RNA 25

Small Cajal body specific RNA 25

Small Cajal body specific RNA 25 (otherwise known as scaRNA25, HBI-100, MBI-100 and MBI-114) is a scaRNA which are a class of ncRNAs characterised as a small nuclear RNAs localised to the Cajal bodies [cite journal | last = Darzacq | first = X | coauthors = Jady BE, Verheggen C, Kiss AM, Bertrand E, Kiss T | year = 2002 | title = Cajal body-specific small nuclear RNAs: a novel class of 2'-O-methylation and pseudouridylation guide RNAs | journal = EMBO J. | volume = 21 | pages = 2746–2756 | pmid = 12032087 | doi = 10.1093/emboj/21.11.2746] . ScaRNA25 was originally identified in a large scale cloning project in mouse cite journal | last = Huttenhofer | first = A | coauthors = Kiefmann M, Meier-Ewert S, O'Brien J, Lehrach H, Bachellerie JP, Brosius J | year = 2001 | title = RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse | journal = EMBO J. | volume = 20 | pages = 2943–2953 | pmid = 11387227 | doi = 10.1093/emboj/20.11.2943] . Later sequence analysis predicted that this RNA guides the pseudouridylation of position U40 in the U6 snRNA .

References

External links

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* [http://www-snorna.biotoul.fr/plus.php?id=HBI-100 snoRNAbase entry for HBI-100]


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