U12 minor spliceosomal RNA
- U12 minor spliceosomal RNA
U12 minor spliceosomal RNA is formed from U12 small nuclear (snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns. Although the U12 sequence is very divergent from that of U2, the two are functionally analogous.[cite journal | last = Tarn | first = WY | coauthors = Steitz JA | year = 1997 | title = Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge | journal = Trends Biochem Sci | volume = 22 | pages = 132–137 | pmid = 9149533 | doi = 10.1016/S0968-0004(97)01018-9] The predicted secondary structure of U12 RNA is published,][cite journal | last = Otake | first = LR | coauthors = Scamborova P, Hashimoto C, Steitz JA | year = 2002 | title = The divergent U12-type spliceosome is required for pre-mRNA splicing and is essential for development in Drosophila | journal = Mol Cell | volume = 9 | pages = 439–446 | pmid = 11864616 | doi = 10.1016/S1097-2765(02)00441-0] ]References
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U4atac minor spliceosomal RNA — is a ncRNA which is an essential component of the minor U12 type spliceosome complex. The U12 type spliceosome is required for removal of the rarer class of eukaryotic introns (AT AC, U12 type) cite journal |author= Lorkovic ZJ, Lehner R,… … Wikipedia
U6atac minor spliceosomal RNA — is a non coding RNA which is an essential component of the minor U12 type spliceosome complex. The U12 type spliceosome is required for removal of the rarer class of eukaryotic introns (AT AC, U12 type) cite journal |author= Lorkovic ZJ, Lehner R … Wikipedia
Small Cajal body specific RNA 20 — In molecular biology, Small Cajal body specific RNA 20 (also known as scaRNA20 or ACA66) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA. scaRNAs are a specific… … Wikipedia
Small Cajal body specific RNA 21 — In molecular biology, Small Cajal body specific RNA 21 (also known as scaRNA21 or ACA68) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA. scaRNAs are a specific… … Wikipedia
Minor spliceosome — The minor spliceosome is a ribonucleoprotein complex that catalyses the removal (splicing) of an atypical class of spliceosomal introns (U12 type) from eukaryotic messenger RNAs in plant, insects, vertebrates and some fungi (Rhizopus oryzae).… … Wikipedia
RNA splicing — In molecular biology and genetics, splicing is a modification of an RNA after transcription, in which introns are removed and exons are joined. This is needed for the typical eukaryotic messenger RNA before it can be used to produce a correct… … Wikipedia
ARN splicéosomal U4atac — Un ARNsn U4atac. Les parties rouges sont les parties invariantes. L’ARN splicéosomal U4atac est un petit ARN nucléaire (snRNA ou ARNpn) non codant entrant dans la composition des petites ribonucléoprotéines nucléaires U4atac. Il est une… … Wikipédia en Français
ARN splicéosomal U6atac — Un ARNsn U6atac. Les parties rouges sont les parties invariantes. L’ARN splicéosomal U6atac est un petit ARN nucléaire (snRNA ou ARNpn) non codant entrant dans la composition des petites ribonucléoprotéines nucléaires U6atac. Il est une… … Wikipédia en Français
SF3B1 — Splicing factor 3b, subunit 1, 155kDa, also known as SF3B1, is a human gene.cite web | title = Entrez Gene: SF3B1 splicing factor 3b, subunit 1, 155kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=23451| … Wikipedia
LSm — s.The Sm proteins were first discovered as antigens in a patient with a form of systemic lupus erythematosus (SLE), a debilitating autoimmune disease. They were named Sm proteins in honor of this patient, Stephanie Smith. Other proteins with very … Wikipedia
