Sex assignment

Sex assignment

Sex assignment refers to the assigning (naming) of the biological sex at the birth of a baby.[1] In the majority of births, a relative, midwife, or physician inspects the genitalia when the baby is delivered, sees ordinary male or female genitalia, and declares, "it's a girl" or "it's a boy" without the expectation of ambiguity.[2] Assignment may also be done prior to birth through prenatal sex discernment. The assignment is perceived as a recognition of an essential aspect of a baby, apparent to everyone. In nearly all cases, usually without conscious deliberation, the parents rear the child as a member of the assigned sex/gender.

The act of assignment is a social act, and is in nearly all cases, and all societies, an act that seems a simple recognition of a simple biological reality. However, the usual act of assignment carries with it some conscious and unconscious assumptions, namely that the external genitalia reflect other aspects of biological sex, such as internal anatomy, gonads, hormones, and chromosomes. The act of assignment usually carries the implicit expectation that future gender identity will develop in the gender of anatomy, assignment, and rearing.[3]

In a minority of cases, the assigned sex or one or more of these related assumptions prove to be false. In the case of some transgender individuals or intersex individuals, gender identity does not simply follow the assigned sex or sex of rearing.[4] There have also been rare instances where parents (for a variety of reasons) have reared an anatomically typical child in the opposite gender. In some conditions usually termed intersex, internal anatomy may not be consistent with assumptions based on external anatomy.[5]


Assignment in intersex conditions

Intersex is a broadly defined term that usually denotes the presence of discordance of the biological aspects of sex: at least some aspect of the genitalia, internal organs, gonadal tissue, or chromosomes is more typical of the other sex, or incompletely differentiated. When the external genitalia appear to be "in between", they are described as ambiguous.[6]

In approximately 1 in 5,000 infants there is enough variation in the appearance of the external genitalia to give rise to hesitation about appropriate assignment by the physician involved. Typical examples would be an unusually prominent clitoris in an otherwise apparently normal girl, or complete cryptorchidism or mild hypospadias in an otherwise apparently normal boy. In most of these cases, a sex is tentatively assigned and the parents told that tests will be performed to quickly confirm the apparent sex. Typical tests in this situation might include a pelvic ultrasound to detect a uterus, a testosterone or 17-hydroxyprogesterone level, and/or a karyotype. In some of these cases a pediatric endocrinologist is consulted to confirm the tentative sex assignment. The expected assignment is usually confirmed within hours to a couple of days in these cases.

In a much smaller proportion of cases, the process of assignment is more complex, and involves both determining what the biological levels of sex may be as well as choosing the best sex assignment. Approximately 1 in 20,000 infants is born with enough ambiguity that assignment becomes a more drawn-out process of multiple tests and intensive education of the parents about sexual differentiation. In some of these cases, it is clear that the child will face major discordances or abnormalities of anatomy or function as he or she grows up, and deciding upon the sex of assignment is a matter of weighing the advantages and disadvantages of either assignment.

Criteria for assignment in these cases have evolved over the decades, as our understanding of the biological factors and our diagnostic tests have improved, as surgical techniques have changed and potential complications have become clearer, and in response to the outcomes and opinions of adults who have grown up with various intersex conditions.

The following is a brief review of the history of the criteria for sex assignment in intersex cases.

Before the 1950s, assignment was based almost entirely on the appearance of the external genitalia. Although physicians recognized that there were conditions in which the apparent secondary sexual characteristics could develop contrary to the person's sex, and conditions in which the gonadal sex did not match that of the external genitalia, their ability to understand and diagnose such conditions in infancy was too poor to attempt to predict future development in most cases.

In the 1950s, endocrinologists developed a basic understanding of the major intersex conditions: (congenital adrenal hyperplasia (CAH), androgen insensitivity syndrome, mixed gonadal dysgenesis and other chromosomal abnormalities. The discovery of cortisone allowed survival of infants with severe CAH for the first time. New hormone tests and karyotypes allowed more confident diagnosis in infancy and prediction of future development. Surgeons began to devise techniques for repairing the perceived abnormalities of the genitalia. Undescended testes could be retrieved, and hypospadias and chordee usually successfully assigned. A greatly enlarged clitoris could be amputated to the usual size, but attempts to create a penis were unsuccessful. John Money and others observed that children with the same types of intersex condition might have been raised as different sexes, and were more likely to develop a gender identity that matched sex of rearing than sex of chromosomes, gonads, or hormones. He also reported that gender identity was usually developed and "set" by early childhood, such that attempts by parents and doctors to reassign sex at an older age was rarely successful. Endocrinologists and surgeons began to base sex assignment in difficult cases not just on the external genitalia, but on the internal genitalia, on the expected future response to testosterone, and on potential fertility.

In the 1960s, surgical confidence with birth defect advanced, as did the acceptability and experience with adult sex reassignment surgery. Pediatric surgeons attempted and claimed success with reconstruction of infant genitalia, especially enlargement or construction of vaginas. The view of gender as a purely social construction, and gender identity as a result of "nurture" rather than "nature" reached near-universal acceptance, especially among liberal, progressive, and academic portions of Western society. The primary goal of assignment was to choose the sex that would lead to the least inconsistency between external anatomy and psyche (gender identity). This led to the recommendation that any child without a penis could be raised as a girl, taught to be a girl, and would develop a female gender identity, and that this would be the best way to minimize future discrepancy between psyche and external anatomy in those few biologically male infants unfortunate enough to be born with an irreparably defective penis (e.g., cloacal exstrophy), or to lose it to accidental trauma in early infancy. In the John/Joan case, John Money claimed successful reassignment at 17 months of age from male to female of a boy whose penis was destroyed during circumcision (though this claim was later shown to be largely fabricated).

The recommended "rules of assignment" and surgery from the late 1960s until the 1990s were roughly:

  • Any XX infant, no matter how virilized, should be raised as a girl to preserve the chance of future fertility. A large, protruding clitoris should be reduced in size with a nerve-sparing recession or reduction rather than simple amputation.
  • Any undervirilized XY infant should be raised as a boy if the penis could be expected to be large enough to stand to urinate and to insert into a vagina for coitus. If it was too small or too malformed (e.g., cloacal exstrophy) for these functions, it was recommended that the baby be assigned as female, any gonads removed, a vaginal opening surgically constructed, and estrogen provided at puberty.
  • An infant with mixed chromosomes (e.g., mixed gonadal dysgenesis or true hermaphroditism) could be raised either way depending on appearance of genitalia and size of phallus.
  • Gender identity is set by 2 years of age and reassignment after that age should not be attempted unless requested by the patient.

These continued to be the most commonly used criteria for assignment until the mid-1990s with one modification. With the recognition in the late 1970s that many cases of micropenis could be treated with hormones, female assignment for unambiguous micropenis went from "recommended but uncommonly done" to "rarely" done.

In the last decade a number of factors have led to changes in the recommended criteria for assignment and surgery. These factors have included:

  • Dozens of grown intersex patients complained publicly about unsatisfactory sexual function or incongruent gender identity, and criticized infant surgery for intersex conditions. Some have suggested that assignments be made more tentatively and surgery deferred in acknowledgement of the possibility of a desire to change gender when the child is older (see Re-assignment, below)
  • In 1997, the "rest of" David Reimer's story was made public. He was the boy who had lost his penis to a surgical accident at 8 months in 1966, was reassigned from boy to girl at 18 months with further surgery to remove testes and estrogen treatment beginning at age 12. Although John Money had described the reassignment as a success in the 1970s, Reimer went public with his account of continuing to have a male gender identity despite the reassignment to a female sex of rearing. At age 15, Reimer reverted to living as a male. At age 38, he committed suicide.
  • There has been a significant swing in educated opinion back toward the importance of biological factors ("nature") in many aspects of human sexuality.
  • A large proportion of XY infants born with cloacal exstrophy and raised as female from early infancy have requested reassignment to male gender in late childhood and adolescence.

Current recommendations for assignment in cases of intersex and other birth defects of the genitalia:

  • Raise nearly all XX infants with functional ovaries as female.
    • The only rare exception would be completely and unambiguously virilized XX infants with CAH, who might be raised as male with genital surgery deferred.
  • Raise most ambiguous XY infants with testes as male unless the external genitalia are more female than male, marked androgen insensitivity is present, and testes are absent or defective.
    • Raise as male any XY infant with unambiguous micropenis.
    • Raise as male any XY infant with functional testes and normal androgen sensitivity but malformed or absent penis.
  • Raise infants with mixed gonadal tissue, true hermaphroditism, or other chromosomal abnormalities as the sex most consistent with external genitalia, since gonads are usually nonfunctional.
  • Gender identity is set by 1–2 years of age and reassignment after that age should not be attempted unless requested by the patient.

Controversies have continued in this decade over surgical aspects of intersex management, especially indications for surgery and optimal timing, but the revised assignment recommendations have been nearly universally accepted.

Reassignment of sex or gender

Sex reassignment refers to a change in sex and/or gender after an original and presumably definitive assignment in infancy. This event can occur in several circumstances.

  1. An early reassignment may be made to correct a clear error. The most common example of this is when a newborn is assumed to be a boy and assigned as such despite absent testes. If at 1–4 weeks of age it is discovered because of newborn screening, a salt-wasting crisis, or investigation of the cryptorchidism that "he" has ovaries, uterus, an XX karyotype, and CAH, the child is likely to be reassigned as female. When virilization is complete and unambiguous, reassignment may be declined or deferred. Any reassignment after the first month or two is no longer considered an "early reassignment".
  2. There have been cases where a male infant has been reassigned to female at several days, weeks, or months of age because of an irreparable birth defect of the genitalia or loss of the penis to trauma or other accident. This is no longer recommended by most experts in the field because of the publicity surrounding similar failed reassignments which became public in the 1990s, such as that of David Reimer.
  3. There have been rare cases where a child with an intersex condition has rejected a sex of rearing, asserted an opposite gender identity, and requested reassignment. Examples of this have occurred in adolescents with several forms of CAH and 5-alpha-reductase deficiency.
  4. The most common type of reassignment occurs when a child or adult with no detectable intersex condition has the psychology of the opposite sex, claims a different gender identity, and either requests or asserts a new gender. Such a person is described as transgender or transsexual. Therapy and/or surgery to align their body with their sex identity. This may be preformed in adulthood and, in recent years, adolescents.
  5. One case of reassignment occurred with a pair of male ischiopagus conjoined twins who shared one set of male genitalia. On surgical separation, one twin received the male genitalia and the other twin was surgically feminized.

See also


  1. ^ Reiner WG (1997) Sex assignment in the neonate with intersex or inadequate genitalia. Archives of Pediatrics and Adolescent Medicine, Oct;151(10):1044-5. PMID 9343017
  2. ^ Reiner WG (2002). Gender identity and sex assignment: a reappraisal for the 21st century. Adv Exp Med Biol. 2002;511:175-89; discussion 189-97. PMID 12575762
  3. ^ Shaw, Alison; Ardener, Shirley (2005). Changing sex and bending gender, p. 21. Berghahn Books, ISBN 9781845450991
  4. ^ Diamond DA, Burns JP, Mitchell C, Lamb K, Kartashov AI, Retik AB (2006). Sex assignment for newborns with ambiguous genitalia and exposure to fetal testosterone: attitudes and practices of pediatric urologists. J Pediatr. 2006 Apr;148(4):445-9. PMID16647402
  5. ^ Mieszczak J, Houk CP, Lee PA. Assignment of the sex of rearing in the neonate with a disorder of sex development. Curr Opin Pediatr. 2009 Aug;21(4):541-7. PMID: 19444113
  6. ^ Ora Hirsch Pescovitz, Erica A. Eugster (2004). Pediatric endocrinology: mechanisms, manifestations, and management, p. 253. Lippincott Williams & Wilkins, ISBN 9780781740593

External links

Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Sex reassignment — may refer to: * Sex reassignment, changing the sex assignment of an infant or child by parents and doctors, usually because of fuller understanding of an intersex condition. * Sex reassignment, changing the social sex of an older child or adult… …   Wikipedia

  • Assignment Nor'Dyren — is a 1973 science fiction novel by Sydney J. Van Scyoc. This science fiction story can be viewed as an allegorical exploration of an important question regarding human society: why do some humans seem to put their energies into creative endeavors …   Wikipedia

  • sex — 1. The biologic character or quality that distinguishes male and female from one another as expressed by analysis of the individual s gonadal, morphologic (internal and external), chromosomal, and hormonal characteristics. Cf.:gender. 2. The… …   Medical dictionary

  • Changing legal gender assignment in Canada — Procedures for changing legal gender assignment in Canada vary between provinces and territories. Except for Quebec, the information below concerns altering the sex recorded on one s birth certificate, and therefore must be done with regard to… …   Wikipedia

  • Changing legal gender assignment in Brazil — Laws concerning gender identity expression around the world.   Legal identity change …   Wikipedia

  • Same-sex marriage in Canada — Legal recognition of same sex relationships Marriage Argentina Belgium Canada Iceland Netherlands Norway Portugal South Africa Spain Sweden …   Wikipedia

  • Recognition of same-sex unions in Brazil — Legal recognition of same sex relationships Marriage Argentina Belgium Canada Iceland Netherlands Norway Portugal South Africa Spain Sweden …   Wikipedia

  • Mr. Big (Sex and the City) — Mr. Big First appearance Pilot (episode 1.01) Last appearance Sex and the City 2 Created by Candace Bushnell Portrayed by Chris Noth …   Wikipedia

  • Congenital adrenal hyperplasia due to 21-hydroxylase deficiency — Classification and external resources Deficient 21 Hydroxylase can lead to accumulation of 17 Hydroxyprogesterone ICD …   Wikipedia

  • History of intersex surgery — The History of intersex surgery is intertwined with the development of the specialities of pediatric surgery, pediatric urology, and pediatric endocrinology, with our increasingly refined understanding of sexual differentiation, with the… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”