Diphosphate—glycerol phosphotransferase

Diphosphate—glycerol phosphotransferase
diphosphate-glycerol phosphotransferase
Identifiers
EC number 2.7.1.79
CAS number 37278-13-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a diphosphate-glycerol phosphotransferase (EC 2.7.1.79) is an enzyme that catalyzes the chemical reaction

diphosphate + glycerol \rightleftharpoons phosphate + glycerol 1-phosphate

Thus, the two substrates of this enzyme are diphosphate and glycerol, whereas its two products are phosphate and glycerol 1-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is diphosphate:glycerol 1-phosphotransferase. Other names in common use include PPi-glycerol phosphotransferase, and pyrophosphate-glycerol phosphotransferase.

References

  • Stetten MR (1970). "Enzymatic synthesis of glycerol I-phosphate. Elevation in diabetic and fasted animals, compared with glucose-6-phosphatase and related enzyme activities". Biochim. Biophys. Acta. 208 (3): 394–403. PMID 4319153.