Norcodeine

Norcodeine
Norcodeine
Systematic (IUPAC) name
3-methoxy- 6α-hydroxy- 4,5α-epoxy- 7,8-didehydromorphinan
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 467-15-2 YesY
ATC code None
PubChem CID 1255
UNII 32W9P3T4ML N
Chemical data
Formula C17H19NO3 
Mol. mass 285.337 g/mol
 N(what is this?)  (verify)

Norcodeine is an opiate analogue that is the N-demethylated derivative of codeine.

Norcodeine has relatively little opioid activity in its own right,[1] but is formed as a metabolite of codeine following ingestion.[2]


References

  1. ^ Fraser HF, Isbell H, Van Horn GD. Human pharmacology and addiction liability of norcodeine. Journal of Pharmacology and Experimental Therapeutics. 1960 Jun;129:172-7. PMID 13824628
  2. ^ Posey BL, Kimble SN. High-performance liquid chromatographic study of codeine, norcodeine, and morphine as indicators of codeine ingestion. Journal of Analytical Toxicology. 1984 Mar-Apr;8(2):68-74. PMID 6716978.

Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Codeine — For other uses, see Codeine (disambiguation). Codeine Systematic (IUPAC) name (5α,6α) 7,8 didehydro 4,5 epoxy 3 methoxy 17 methylmorphinan 6 ol Cli …   Wikipedia

  • Opioid — Endogenous opioid peptides Skeletal molecular images Adrenorphin Amidorphin Casomorphin …   Wikipedia

  • Morphine — This article is about the drug. For other meanings, see Morphine (disambiguation). Morphia redirects here. For other uses, see Morphia (disambiguation). Not to be confused with Morphinae, Morphea, or Morpholine. Morphine …   Wikipedia

  • Opiate — For other uses see Opiate (disambiguation), or for the class of drugs see Opioid. Harvesting the poppy pod. In medicine, the term opiate describes any of the narcotic opioid alkaloids found as natural products in the opium poppy plant …   Wikipedia

  • Phencyclidine — Systematic (IUPAC) name …   Wikipedia

  • Loperamide — Imodium redirects here. For the song by Nirvana, see Breed (song). Loperamide Systematic (IUPAC) name …   Wikipedia

  • Pethidine — Systematic (IUPAC) name …   Wikipedia

  • Opioid receptor — Opioid receptors are a group of G protein coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are 40% identical to somatostatin… …   Wikipedia

  • Oxymorphone — Systematic (IUPAC) name 4,5α epoxy 3,14 dihydroxy 17 methylmorphinan 6 one Clinical data Trade names …   Wikipedia

  • Sufentanil — Systematic (IUPAC) name N [4 (methoxymethyl) …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”