- Isopropamide
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Isopropamide Systematic (IUPAC) name 4-amino-N,N-diisopropyl-N-methyl-4-oxo-3,3-diphenylbutan-1-aminium Clinical data MedlinePlus a694006 Pregnancy cat. ? Legal status ? (US) Unscheduled Routes Oral Identifiers CAS number 71-81-8 ATC code A03AB09 PubChem CID 3775 DrugBank DB01625 ChemSpider 3643 UNII 8B9I31H724 ChEMBL CHEMBL1201232 Chemical data Formula C23H33N2O1 + Mol. mass 353.52092 g/mol SMILES eMolecules & PubChem (what is this?) (verify) Isopropamide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.
References
- Seeherman R, Isopropamide iodide: a long-acting anticholinergic, Del Med J. 1957 Oct;29(10):265-9.
- Boss EG Jr, Buchanan GC, Effect of isopropamide iodide on basal gastric secretion in the human, Gastroenterology. 1957 Nov;33(5):730-6.
Drugs for functional gastrointestinal disorders (A03) Drugs for
functional bowel disordersTertiary
amino groupQuaternary ammonium
compoundsBenzilone • Mepenzolate • Pipenzolate • Glycopyrronium • Oxyphenonium • Penthienate • Methantheline • Propantheline • Otilonium bromide • Tridihexethyl • Isopropamide • Hexocyclium • Poldine • Bevonium • Diphemanil • Tiemonium iodide • Prifinium bromide • Timepidium bromide • FenpiveriniumActing on serotonin receptorsOtherFenpiprane • Diisopromine • Chlorbenzoxamine • Pinaverium • Fenoverine • Idanpramine • Proxazole • Alverine • Trepibutone • Isometheptene • Caroverine • Phloroglucinol • Silicones • TrimethyldiphenylpropylamineBelladonna and derivatives
(antimuscarinics)tertiary amines: Atropine • Hyoscyamine
quaternary ammonium compounds: Scopolamine (Butylscopolamine, Methylscopolamine) • Methylatropine • Fentonium • Cimetropium bromidePropulsives This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.