Deoxycytidine deaminase

deoxycytidine deaminase
Identifiers
EC number	3.5.4.14
CAS number	37259-56-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a deoxycytidine deaminase (EC 3.5.4.14) is an enzyme that catalyzes the chemical reaction

deoxycytidine + H₂O $\rightleftharpoons$ deoxyuridine + NH₃

Thus, the two substrates of this enzyme are deoxycytidine and H₂O, whereas its two products are deoxyuridine and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is deoxycytidine aminohydrolase. This enzyme participates in pyrimidine metabolism.

References

• Cohen SS (1953). "Studies on controlling mechanisms in the metabolism of virus-infected bacteria". Cold Spring Harbour Symp. Quant. Biol. 18: 221–235. 

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