N-sulfoglucosamine sulfohydrolase

N-sulfoglucosamine sulfohydrolase
N-sulfoglucosamine sulfohydrolase
Identifiers
EC number 3.10.1.1
CAS number 37289-41-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a N-sulfoglucosamine sulfohydrolase (EC 3.10.1.1) is an enzyme that catalyzes the chemical reaction

N-sulfo-D-glucosamine + H2O \rightleftharpoons D-glucosamine + sulfate

Thus, the two substrates of this enzyme are N-sulfo-D-glucosamine and H2O, whereas its two products are D-glucosamine and sulfate.

This enzyme belongs to the family of hydrolases, specifically those acting on sulfur-nitrogen bonds. The systematic name of this enzyme class is N-sulfo-D-glucosamine sulfohydrolase. Other names in common use include sulfoglucosamine sulfamidase, heparin sulfamidase, 2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate, and sulphohydrolase). This enzyme participates in glycosaminoglycan degradation and glycan structures - degradation.

References