N-sulfoglucosamine-3-sulfatase

N-sulfoglucosamine-3-sulfatase
Identifiers
EC number	3.1.6.15
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles

In enzymology, a N-sulfoglucosamine-3-sulfatase (EC 3.1.6.15) is an enzyme that catalyzes the chemical reaction of cleaving off the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is N-sulfo-3-sulfoglucosamine 3-sulfohydrolase. This enzyme is also called chondroitinsulfatase. This enzyme participates in the degradtaion of glycan structures.

References

• Bruce JS, McLean MW, Long WF, Williamson FB (1985). "Flavobacterium heparinum 3-O-sulphatase for N-substituted glucosamine 3-O-sulphate". Eur. J. Biochem. 148 (2): 359–65. doi:10.1111/j.1432-1033.1985.tb08847.x. PMID 3987694. 
• Leder IG (1980). "A novel 3-O sulfatase from human urine acting on methyl-2-deoxy-2-sulfamino-alphs-D-glucopyranoside 3-sulfate". Biochem. Biophys. Res. Commun. 94 (4): 1183–9. doi:10.1016/0006-291X(80)90544-6. PMID 7396957. 

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This hydrolase article is a stub. You can help Wikipedia by expanding it.v · Categories: Hydrolase stubs EC 3.1.6 Enzymes of unknown structure Wikimedia Foundation. 2010. Игры ⚽ Нужна курсовая? Prenyl-diphosphatase Ibăneasa River Look at other dictionaries: Sulfatase — Pfam box Symbol = Sulfatase Name = width =200 caption =Steryl sulfatase Pfam= PF00884 InterPro= IPR000917 SMART= PROSITE = PDOC00117 SCOP = 1auk TCDB = OPM family= 24 OPM protein= 1p49 PDB=PDB3|1fsu :43 486 PDB3|1hdhB:3 501 PDB3|1p49A:25… …   Wikipedia Disulfoglucosamine-6-sulfatase — Identifiers EC number 3.1.6.11 CAS number 37288 32 7 …   Wikipedia heparan N-sulfatase — An enzyme that participates in the stepwise degradation of heparan sulfate; heparan N sulfatase hydrolyzes the sulfate moiety attached to the amino group of the glucosamine residue of heparan sulfate; a deficiency of this enzyme is associated… …   Medical dictionary N-sulfoglucosamine sulfohydrolase — N sul·fo·glu·cos·amine sul·fo·hy·dro·lase (sul″fo gloo kōsґə mēn sul″fo hiґdro lās) [EC 3.10.1.1] an enzyme of the hydrolase class that catalyzes the cleavage of sulfate groups from the amino groups of sulfated… …   Medical dictionary List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… …   Wikipédia en Français SGSH — N sulfoglucosamine sulfohydrolase (sulfamidase), also known as SGSH, is a human gene.cite web | title = Entrez Gene: SGSH N sulfoglucosamine sulfohydrolase (sulfamidase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia Maladie De Sanfilippo — La maladie de Sanfillipo ou syndrome de Sanfillipo est une mucopolysaccharidose qui est due à une déficience en une enzyme lysosomiale, la héparane N sulfatase. Cette enzyme réalise une étape cruciale du catabolisme du sulfate d héparane, un… …   Wikipédia en Français Maladie de Sanfilippo — La maladie de Sanfillipo ou syndrome de Sanfillipo est une mucopolysaccharidose qui est due à une déficience en une enzyme lysosomiale, la héparane N sulfatase. Cette enzyme réalise une étape cruciale du catabolisme du sulfate d héparane, un… …   Wikipédia en Français 18+ © Academic, 2000-2025 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”