- Disulfoglucosamine-6-sulfatase
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disulfoglucosamine-6-sulfatase Identifiers EC number 3.1.6.11 CAS number 37288-32-7 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a disulfoglucosamine-6-sulfatase (EC 3.1.6.11) is an enzyme that catalyzes the chemical reaction
- N,6-O-disulfo-D-glucosamine + H2O N-sulfo-D-glucosamine + sulfate
Thus, the two substrates of this enzyme are N,6-O-disulfo-D-glucosamine and H2O, whereas its two products are N-sulfo-D-glucosamine and sulfate.
This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is N,6-O-disulfo-D-glucosamine 6-sulfohydrolase. Other names in common use include N-sulfoglucosamine-6-sulfatase, and 6,N-disulfoglucosamine 6-O-sulfohydrolase.
References
- Dietrich CP (1969). "Enzymic degradation of heparin. A sulphamidase and a sulphoesterase from Flavobacterium heparinum". Biochem. J. 111 (1): 91–5. PMC 1187498. PMID 5775690. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1187498.
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