Oxaloacetase

Oxaloacetase
oxaloacetase
Identifiers
EC number 3.7.1.1
CAS number 9024-89-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an oxaloacetase (EC 3.7.1.1) is an enzyme that catalyzes the chemical reaction

oxaloacetate + H2O \rightleftharpoons oxalate + acetate

Thus, the two substrates of this enzyme are oxaloacetate and H2O, whereas its two products are oxalate and acetate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is oxaloacetate acetylhydrolase. This enzyme is also called oxalacetic hydrolase.

References

  • Hayaishi O, Shimazono H, Katagiri M and Saito Y (1956). "Enzymatic formation of oxalate and acetate from oxaloacetate". J. Am. Chem. Soc. 78: 5126–5127. doi:10.1021/ja01600a084.