- KLK2
Kallikrein-related peptidase 2, also known as KLK2, is a human
gene . [cite web | title = Entrez Gene: KLK2 Kallikrein-related peptidase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3817| accessdate = ]PBB_Summary
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summary_text =References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Riegman PH, Vlietstra RJ, van der Korput HA, "et al." |title=Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species. |journal=Mol. Cell. Endocrinol. |volume=76 |issue= 1-3 |pages= 181–90 |year= 1992 |pmid= 1726490 |doi=
*cite journal | author=Qin H, Kemp J, Yip MY, "et al." |title=Localization of human glandular kallikrein-1 gene to chromosome 19q13.3-13.4 by in situ hybridization. |journal=Hum. Hered. |volume=41 |issue= 4 |pages= 222–6 |year= 1992 |pmid= 1783409 |doi=
*cite journal | author=Riegman PH, Vlietstra RJ, Klaassen P, "et al." |title=The prostate-specific antigen gene and the human glandular kallikrein-1 gene are tandemly located on chromosome 19. |journal=FEBS Lett. |volume=247 |issue= 1 |pages= 123–6 |year= 1989 |pmid= 2468530 |doi=
*cite journal | author=Schedlich LJ, Bennetts BH, Morris BJ |title=Primary structure of a human glandular kallikrein gene. |journal=DNA |volume=6 |issue= 5 |pages= 429–37 |year= 1988 |pmid= 2824146 |doi=
*cite journal | author=Frenette G, Deperthes D, Tremblay RR, "et al." |title=Purification of enzymatically active kallikrein hK2 from human seminal plasma. |journal=Biochim. Biophys. Acta |volume=1334 |issue= 1 |pages= 109–15 |year= 1997 |pmid= 9042371 |doi=
*cite journal | author=Bourgeois L, Brillard-Bourdet M, Deperthes D, "et al." |title=Serpin-derived peptide substrates for investigating the substrate specificity of human tissue kallikreins hK1 and hK2. |journal=J. Biol. Chem. |volume=272 |issue= 47 |pages= 29590–5 |year= 1997 |pmid= 9368023 |doi=
*cite journal | author=Mikolajczyk SD, Millar LS, Kumar A, Saedi MS |title=Human glandular kallikrein, hK2, shows arginine-restricted specificity and forms complexes with plasma protease inhibitors. |journal=Prostate |volume=34 |issue= 1 |pages= 44–50 |year= 1998 |pmid= 9428387 |doi=
*cite journal | author=Yu DC, Sakamoto GT, Henderson DR |title=Identification of the transcriptional regulatory sequences of human kallikrein 2 and their use in the construction of calydon virus 764, an attenuated replication competent adenovirus for prostate cancer therapy. |journal=Cancer Res. |volume=59 |issue= 7 |pages= 1498–504 |year= 1999 |pmid= 10197620 |doi=
*cite journal | author=Mikolajczyk SD, Millar LS, Kumar A, Saedi MS |title=Prostatic human kallikrein 2 inactivates and complexes with plasminogen activator inhibitor-1. |journal=Int. J. Cancer |volume=81 |issue= 3 |pages= 438–42 |year= 1999 |pmid= 10209959 |doi=
*cite journal | author=Lövgren J, Valtonen-André C, Marsal K, "et al." |title=Measurement of prostate-specific antigen and human glandular kallikrein 2 in different body fluids. |journal=J. Androl. |volume=20 |issue= 3 |pages= 348–55 |year= 1999 |pmid= 10386814 |doi=
*cite journal | author=Cargill M, Altshuler D, Ireland J, "et al." |title=Characterization of single-nucleotide polymorphisms in coding regions of human genes. |journal=Nat. Genet. |volume=22 |issue= 3 |pages= 231–8 |year= 1999 |pmid= 10391209 |doi= 10.1038/10290
*cite journal | author=Lövgren J, Airas K, Lilja H |title=Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors. |journal=Eur. J. Biochem. |volume=262 |issue= 3 |pages= 781–9 |year= 1999 |pmid= 10411640 |doi=
*cite journal | author=Mikolajczyk SD, Millar LS, Marker KM, "et al." |title=Identification of a novel complex between human kallikrein 2 and protease inhibitor-6 in prostate cancer tissue. |journal=Cancer Res. |volume=59 |issue= 16 |pages= 3927–30 |year= 1999 |pmid= 10463585 |doi=
*cite journal | author=Liu XF, Essand M, Vasmatzis G, "et al." |title=Identification of three new alternate human kallikrein 2 transcripts: evidence of long transcript and alternative splicing. |journal=Biochem. Biophys. Res. Commun. |volume=264 |issue= 3 |pages= 833–9 |year= 1999 |pmid= 10544017 |doi= 10.1006/bbrc.1999.1595
*cite journal | author=Ren F, Zhang S, Mitchell SH, "et al." |title=Tea polyphenols down-regulate the expression of the androgen receptor in LNCaP prostate cancer cells. |journal=Oncogene |volume=19 |issue= 15 |pages= 1924–32 |year= 2000 |pmid= 10773882 |doi= 10.1038/sj.onc.1203511
*cite journal | author=Harvey TJ, Hooper JD, Myers SA, "et al." |title=Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4. |journal=J. Biol. Chem. |volume=275 |issue= 48 |pages= 37397–406 |year= 2001 |pmid= 10969073 |doi= 10.1074/jbc.M004525200
*cite journal | author=Chen VC, Chao L, Chao J |title=A positively charged loop on the surface of kallistatin functions to enhance tissue kallikrein inhibition by acting as a secondary binding site for kallikrein. |journal=J. Biol. Chem. |volume=275 |issue= 51 |pages= 40371–7 |year= 2001 |pmid= 10991942 |doi= 10.1074/jbc.M005691200
*cite journal | author=Gan L, Lee I, Smith R, "et al." |title=Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. |journal=Gene |volume=257 |issue= 1 |pages= 119–30 |year= 2001 |pmid= 11054574 |doi=
*cite journal | author=Réhault S, Monget P, Mazerbourg S, "et al." |title=Insulin-like growth factor binding proteins (IGFBPs) as potential physiological substrates for human kallikreins hK2 and hK3. |journal=Eur. J. Biochem. |volume=268 |issue= 10 |pages= 2960–8 |year= 2001 |pmid= 11358513 |doi=
*cite journal | author=Saedi MS, Zhu Z, Marker K, "et al." |title=Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells. |journal=Int. J. Cancer |volume=94 |issue= 4 |pages= 558–63 |year= 2002 |pmid= 11745444 |doi=PBB_Controls
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