P-benzoquinone reductase (NADPH)

p-benzoquinone reductase (NADPH)
Identifiers
EC number	1.6.5.6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a p-benzoquinone reductase (NADPH) (EC 1.6.5.6) is an enzyme that catalyzes the chemical reaction

NADPH + H⁺ + p-benzoquinone $\rightleftharpoons$ NADP⁺ + hydroquinone

The 3 substrates of this enzyme are NADPH, H⁺, and p-benzoquinone, whereas its two products are NADP⁺ and hydroquinone.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with a quinone or similar compound as acceptor. The systematic name of this enzyme class is NADPH:p-benzoquinone oxidoreductase. This enzyme participates in gamma-hexachlorocyclohexane degradation.

References

• Spain JC, Gibson DT (1991). "Pathway for Biodegradation of p-Nitrophenol in a Moraxella sp". Appl. Environ. Microbiol. 57 (3): 812–819. PMC 182799. PMID 16348446. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=182799. 

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