Succinate-semialdehyde dehydrogenase (NAD(P)+)
- Succinate-semialdehyde dehydrogenase (NAD(P)+)
In enzymology, a succinate-semialdehyde dehydrogenase [NAD(P)+] (EC number|1.2.1.16) is an enzyme that catalyzes the chemical reaction
:succinate semialdehyde + NAD(P)+ + H2O succinate + NAD(P)H + 2 H+
The 4 substrates of this enzyme are succinate semialdehyde, NAD+, NADP+, and H2O, whereas its 4 products are succinate, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is succinate-semialdehyde:NAD(P)+ oxidoreductase. Other names in common use include succinate semialdehyde dehydrogenase (nicotinamide adenine, dinucleotide (phosphate)), and succinate-semialdehyde dehydrogenase [NAD(P)+] . This enzyme participates in 3 metabolic pathways: glutamate metabolism, tyrosine metabolism, and butanoate metabolism.
References
* Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 203-221.
*
*
External links
::"The CAS registry number for this enzyme class is CAS registry|37250-88-7."
Gene Ontology (GO) codes
Wikimedia Foundation.
2010.
Look at other dictionaries:
Succinate-semialdehyde dehydrogenase — In enzymology, a succinate semialdehyde dehydrogenase (EC number|1.2.1.24) is an enzyme that catalyzes the chemical reaction:succinate semialdehyde + NAD+ + H2O ightleftharpoons succinate + NADH + 2 H+The 3 substrates of this enzyme are succinate … Wikipedia
succinate semialdehyde — An intermediate in the catabolism of γ aminobutyrate. s. dehydrogenase an enzyme that catalyzes the reaction of s. and either NAD+ or NADP+ to form succinate and NADH (or NADPH); a deficiency of this … Medical dictionary
4-hydroxybutyrate dehydrogenase — In enzymology, a 4 hydroxybutyrate dehydrogenase (EC number|1.1.1.61) is an enzyme that catalyzes the chemical reaction:4 hydroxybutanoate + NAD+ ightleftharpoons succinate semialdehyde + NADH + H+The two substrates of this enzyme are therefore 4 … Wikipedia
List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH … Wikipedia
ALDH5A1 (gene) — Aldehyde dehydrogenase 5 family, member A1 (succinate semialdehyde dehydrogenase), also known as ALDH5A1, is a human gene.cite web | title = Entrez Gene: ALDH5A1 aldehyde dehydrogenase 5 family, member A1 (succinate semialdehyde dehydrogenase)|… … Wikipedia
Creatine kinase — Crystals of creatine kinase Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phospho creatine kinase (and sometimes incorrectly as creatinine kinase), is an enzyme (EC 2.7.3.2) expressed by various tissues and cell types. CK… … Wikipedia
Citrate — The citrate anion A citrat … Wikipedia
Oxaloacetic acid — Oxaloacetic acid … Wikipedia
List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… … Wikipedia
