Succinate-semialdehyde dehydrogenase
- Succinate-semialdehyde dehydrogenase
In enzymology, a succinate-semialdehyde dehydrogenase (EC number|1.2.1.24) is an enzyme that catalyzes the chemical reaction
:succinate semialdehyde + NAD+ + H2O succinate + NADH + 2 H+
The 3 substrates of this enzyme are succinate semialdehyde, NAD+, and H2O, whereas its 3 products are succinate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is succinate-semialdehyde:NAD+ oxidoreductase. Other names in common use include succinate semialdehyde dehydrogenase, succinic semialdehyde dehydrogenase, succinyl semialdehyde dehydrogenase, and succinate semialdehyde:NAD+ oxidoreductase. This enzyme participates in glutamate and butanoate metabolism.
References
*
External links
::"The CAS registry number for this enzyme class is CAS registry|9028-95-9."
Gene Ontology (GO) codes
Wikimedia Foundation.
2010.
Look at other dictionaries:
Succinate-semialdehyde dehydrogenase (NAD(P)+) — In enzymology, a succinate semialdehyde dehydrogenase [NAD(P)+] (EC number|1.2.1.16) is an enzyme that catalyzes the chemical reaction:succinate semialdehyde + NAD(P)+ + H2O ightleftharpoons succinate + NAD(P)H + 2 H+The 4 substrates of this… … Wikipedia
succinate-semialdehyde dehydrogenase deficiency — suc·ci·nate semi·al·de·hyde de·hy·dro·gen·ase de·fi·cien·cy (sukґsĭ nāt sem″e alґdə hīd de hiґdro jən ās) an autosomal recessive aminoacidopathy caused by mutation in the succinate semialdehyde dehydrogenase… … Medical dictionary
succinate-semialdehyde dehydrogenase — suc·ci·nate semi·al·de·hyde de·hy·dro·gen·ase (sukґsĭ nāt sem″e alґdə hīd de hiґdro jən ās) [EC 1.2.1.24] an enzyme of the oxidoreductase class that catalyzes the oxidation of γ hydroxybutyric acid to… … Medical dictionary
Succinic semialdehyde dehydrogenase deficiency — Infobox Disease Name = PAGENAME Caption = Gamma Hydroxybutyric acid DiseasesDB = 29825 ICD10 = ICD9 = ICDO = OMIM = 271980 MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = Succinic semialdehyde dehydrogenase deficiency (SSADHD), also known … Wikipedia
succinate semialdehyde — An intermediate in the catabolism of γ aminobutyrate. s. dehydrogenase an enzyme that catalyzes the reaction of s. and either NAD+ or NADP+ to form succinate and NADH (or NADPH); a deficiency of this … Medical dictionary
4-hydroxybutyrate dehydrogenase — In enzymology, a 4 hydroxybutyrate dehydrogenase (EC number|1.1.1.61) is an enzyme that catalyzes the chemical reaction:4 hydroxybutanoate + NAD+ ightleftharpoons succinate semialdehyde + NADH + H+The two substrates of this enzyme are therefore 4 … Wikipedia
ALDH5A1 (gene) — Aldehyde dehydrogenase 5 family, member A1 (succinate semialdehyde dehydrogenase), also known as ALDH5A1, is a human gene.cite web | title = Entrez Gene: ALDH5A1 aldehyde dehydrogenase 5 family, member A1 (succinate semialdehyde dehydrogenase)|… … Wikipedia
List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH … Wikipedia
γ-hydroxybutyric acid — (GHB) butyric acid substituted at the γ, or 4, position; it is an intermediate in the metabolism of γ aminobutyric acid (GABA) and with GABA occurs at elevated levels in some body fluids in succinate semialdehyde dehydrogenase… … Medical dictionary
NCS-382 — IUPAC name (2E) (5 hydroxy 5,7,8,9 tetrahydro 6H benzo[a][7]annulen 6 ylidene ethanoic acid … Wikipedia