Formate dehydrogenase (NADP+)
- Formate dehydrogenase (NADP+)
In enzymology, a formate dehydrogenase (NADP+) (EC number|1.2.1.43) is an enzyme that catalyzes the chemical reaction
:formate + NADP+ CO2 + NADPH
Thus, the two substrates of this enzyme are formate and NADP+, whereas its two products are CO2 and NADPH.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is formate:NADP+ oxidoreductase. Other names in common use include NADP+-dependent formate dehydrogenase, and formate dehydrogenase (NADP+). This enzyme participates in methane metabolism. It has 3 cofactors: iron, Tungsten, and Selenium.
tructural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2GSD.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|51377-43-6."
Gene Ontology (GO) codes
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