Morpheridine

Morpheridine

Systematic (IUPAC) name
ethyl 1-(2-morpholin-4-ylethyl)-4-phenyl-piperidine-4-carboxylate
Clinical data
Pregnancy cat.	?
Legal status	CD (UK) Schedule I (US) international schedule I
Identifiers
CAS number	469-81-8 Y
ATC code	None
PubChem	CID 61121
ChemSpider	55069 Y
UNII	1854GKB41Y Y
Chemical data
Formula	C20H30N2O3
Mol. mass	346.46 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C20H30N2O3/c1-2-25-19(23)20(18-6-4-3-5-7-18)8-10-21(11-9-20)12-13-22-14-16-24-17-15-22/h3-7H,2,8-17H2,1H3 Y Key:JDEDMCKQPKGSAX-UHFFFAOYSA-N Y
Y(what is this?)  (verify)

Morpheridine (Morpholinoethylnorpethidine)^[1] is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine). It is a strong analgesic with around 4 times the potency of pethidine,^[2] and unlike pethidine, does not cause convulsions, although it produces the standard opioid side effects such as sedation and respiratory depression.^[3]

Morpheridine is not currently used in medicine and is a Schedule I drug which is controlled under UN drug conventions.^[4]

References

1. ^ US 2795581, STERN EDWARD S; ANDERSON RONALD J, "Piperidine Compounds and Their Production", issued 06/11/1957, assigned to J.F. McFarlan & Co 
2. ^ Holmes, J. M. (1958). "Morpholinoethylnorpethidine hydrochloride in obstetrics". The Journal of obstetrics and gynaecology of the British Empire 65 (1): 98–99. PMID 13514558.  edit
3. ^ Green, A. F.; Ward, N. B. (1956). "Analgesic and other properties of morpholinoethylnorpethidine". British journal of pharmacology and chemotherapy 11 (1): 32–34. PMC 1509567. PMID 13304251. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1509567.  edit
4. ^ "Single convention on drugs 1961". http://www.ukcia.org/pollaw/lawlibrary/singleconventiononnarcoticdrugs1961.php. 

This analgesic-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Synthetic opioids Morpholines Piperidines Ethyl esters Mu-opioid agonists Analgesic stubs Wikimedia Foundation. 2010. Игры ⚽ Поможем решить контрольную работу List of Thessalonians Landesliga Bayern-Mitte Look at other dictionaries: morpheridine — noun A strong analgesic, a 4 phenylpiperidine derivative related to pethidine …   Wiktionary Opioid — Endogenous opioid peptides Skeletal molecular images Adrenorphin Amidorphin Casomorphin …   Wikipedia Morphine — This article is about the drug. For other meanings, see Morphine (disambiguation). Morphia redirects here. For other uses, see Morphia (disambiguation). Not to be confused with Morphinae, Morphea, or Morpholine. Morphine …   Wikipedia Opiate — For other uses see Opiate (disambiguation), or for the class of drugs see Opioid. Harvesting the poppy pod. In medicine, the term opiate describes any of the narcotic opioid alkaloids found as natural products in the opium poppy plant …   Wikipedia Phencyclidine — Systematic (IUPAC) name …   Wikipedia Loperamide — Imodium redirects here. For the song by Nirvana, see Breed (song). Loperamide Systematic (IUPAC) name …   Wikipedia Pethidine — Systematic (IUPAC) name …   Wikipedia Opioid receptor — Opioid receptors are a group of G protein coupled receptors with opioids as ligands.[1][2][3] The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are 40% identical to somatostatin… …   Wikipedia Oxymorphone — Systematic (IUPAC) name 4,5α epoxy 3,14 dihydroxy 17 methylmorphinan 6 one Clinical data Trade names …   Wikipedia Sufentanil — Systematic (IUPAC) name N [4 (methoxymethyl) …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”