Acute aortic syndrome

Acute aortic syndrome

Acute aortic syndrome (AAS) describes a range of severe, painful, potentially life-threatening abnormalities of the aorta.cite journal |author=Ahmad F, Cheshire N, Hamady M |title=Acute aortic syndrome: pathology and therapeutic strategies |journal=Postgrad Med J |volume=82 |issue=967 |pages=305–12 |year=2006 |month=May |pmid=16679467 |doi=10.1136/pgmj.2005.043083 |url=http://pmj.bmjjournals.com/cgi/pmidlookup?view=long&pmid=16679467] These include aortic dissection, intramural thrombus, and penetrating atherosclerotic aortic ulcer.cite journal | last=Macura | first=KJ | coauthors=Corl FM, Fishman EK, Bluemke DA | title=Pathogenesis in acute aortic syndromes: aortic dissection, intramural hematoma, and penetrating atherosclerotic aortic ulcer | journal=American Journal of Roentgenology | volume=181 | issue=2 | pages=309–316 | date=August 2003 | pmid=12876003 | url=http://www.ajronline.org/cgi/content/full/181/2/309 | accessdate=2008-05-28 ] AAS can be caused by a lesion on the wall of the aorta that involves the tunica media, often in the descending aorta.cite journal |author=Evangelista Masip A |title= [Progress in the acute aortic syndrome] |language=Spanish; Castilian |journal=Rev Esp Cardiol |volume=60 |issue=4 |pages=428–39 |year=2007 |month=April |pmid=17521551 | url=http://www.revespcardiol.org/cgi-bin/wdbcgi.exe/cardio/mrevista_cardio.pubmed_full?inctrl=05ZI0113&vol=60&num=4&pag=428] It is possible for AAS to lead to acute coronary syndrome.cite journal |author=Manghat NE, Morgan-Hughes GJ, Roobottom CA |title=Multi-detector row computed tomography: imaging in acute aortic syndrome |journal=Clin Radiol |volume=60 |issue=12 |pages=1256–67 |year=2005 |month=December |pmid=16291307 |doi=10.1016/j.crad.2005.06.011 |url=] The term was introduced in 2001.cite journal |author=van der Loo B, Jenni R |title=Acute aortic syndrome: proposal for a novel classification |journal=Heart |volume=89 |issue=8 |pages=928 |year=2003 |month=August |pmid=12860875 |doi= |url=http://heart.bmj.com/cgi/pmidlookup?view=long&pmid=12860875] cite journal |author=Vilacosta I, Román JA |title=Acute aortic syndrome |journal=Heart |volume=85 |issue=4 |pages=365–8 |year=2001 |month=April |pmid=11250953 |doi= |url=http://heart.bmj.com/cgi/pmidlookup?view=long&pmid=11250953]

Causes

Causes can include aortic dissection, intramural hematoma, penetrating atherosclerotic ulcer or a thoracic aneurysm that has become unstable.cite journal |author=Smith AD, Schoenhagen P |title=CT imaging for acute aortic syndrome |journal=Cleve Clin J Med |volume=75 |issue=1 |pages=7–9, 12, 15–7 passim |year=2008 |month=January |pmid=18236724 |doi= |url=] The potential causes of AAS are life-threatening and present with similar symptoms, making it difficult to distinguish the ultimate cause, though high resolution, high contrast computerised tomography can be used.cite journal |author=Marijon E, Vilanculos A, Tivane A, "et al" |title=Thoracic aortic aneurysm: direct sign of rupture |journal=Cardiovasc J Afr |volume=18 |issue=3 |pages=180–1 |year=2007 |pmid=17612751 |doi= | format = pdf | |url=http://blues.sabinet.co.za/WebZ/Authorize?sessionid=0:autho=pubmed:password=pubmed2004&/AdvancedQuery?&format=F&next=images/ejour/cardio/cardio_v18_n3_a10.pdf]

Diagnosis

The condition can be mimicked by a ruptured cyst of the pericardium,cite journal |author=Nishigami K, Hirayama T, Kamio T |title=Pericardial cyst rupture mimicking acute aortic syndrome |journal=Eur. Heart J. |volume= |issue= |pages= |year=2008 |month=February |pmid=18296680 |doi=10.1093/eurheartj/ehn038 |url=http://eurheartj.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=18296680] ruptured aortic aneurysm and acute coronary syndrome.cite journal |author=Hansen MS, Nogareda GJ, Hutchison SJ |title=Frequency of and inappropriate treatment of misdiagnosis of acute aortic dissection |journal=Am. J. Cardiol. |volume=99 |issue=6 |pages=852–6 |year=2007 |month=March |pmid=17350381 |doi=10.1016/j.amjcard.2006.10.055 |url=http://linkinghub.elsevier.com/retrieve/pii/S0002-9149(06)02407-6]

Misdiagnosis is estimated at 39% and is associated with delays correct diagnosis and improper treatment with anticoagulants producing excessive bleeding and extended hospital stays.cite journal |author=Hansen MS, Nogareda GJ, Hutchison SJ |title=Frequency of and inappropriate treatment of misdiagnosis of acute aortic dissection |journal=Am. J. Cardiol. |volume=99 |issue=6 |pages=852–6 |year=2007 |month=March |pmid=17350381 |doi=10.1016/j.amjcard.2006.10.055 |url=http://linkinghub.elsevier.com/retrieve/pii/S0002-9149(06)02407-6]

Management

AAS is life-threatening, with a high mortality rate if appearing acutely, reduced only when diagnosed early and treated by a surgeon with considerable expertise. If patients survive acute presentation, within three to five years 30% will develop complications and require close follow-up. Early diagnosis is essential for survival and management is challenging though greater awareness of the syndrome and improving management strategies are improving patient outcomes.cite journal |author=Ince H, Nienaber CA |title= [Management of acute aortic syndromes] |language=Spanish; Castilian |journal=Rev Esp Cardiol |volume=60 |issue=5 |pages=526–41 |year=2007 |month=May |pmid=17535765 |doi= |url=http://www.revespcardiol.org/cgi-bin/wdbcgi.exe/cardio/mrevista_cardio.pubmed_full?inctrl=05ZI0113&vol=60&num=5&pag=526]

References


Wikimedia Foundation. 2010.

Поможем написать курсовую

Look at other dictionaries:

  • Aortic dissection — Classification and external resources Dissection of the aorta descendens (3), which starts from the left subclavian artery, reaching to the abdominal aorta (4). Aorta ascendens (1) and aortic arch (2) are not involved …   Wikipedia

  • Aortic insufficiency — See also: mitral regurgitation and tricuspid insufficiency Aortic insufficiency Classification and external resources Micrograph of myxomatous degeneration – a cause of aortic insufficiency …   Wikipedia

  • Aortic valve stenosis — Classification and external resources ICD 10 I35.0, I06.0, Q23.0 …   Wikipedia

  • Aortic aneurysm — Classification and external resources CT reconstruction image of an abdominal aortic aneurysm ICD 10 I …   Wikipedia

  • syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… …   Medical dictionary

  • Acute respiratory distress syndrome — ICD9|518.82 ICDO = Caption = Chest x ray of patient with ARDS OMIM = MedlinePlus = 000103 eMedicineSubj = med eMedicineTopic = 70 DiseasesDB = 892 MeshID = D012128 Acute respiratory distress syndrome (ARDS), also known as respiratory distress… …   Wikipedia

  • Marfan syndrome — Marfan redirects here. For the person after whom the syndrome is named, see Antoine Marfan. Marfan syndrome Classification and external resources Micrograph demonstrating myxomatous degeneration of the aorti …   Wikipedia

  • Abdominal aortic aneurysm — Classification and external resources CT reconstruction image of an abdominal aortic aneurysm ICD 10 I …   Wikipedia

  • Budd–Chiari syndrome — Budd Chiari syndrome Classification and external resources Posterior abdominal wall, after removal of the peritoneum, showing kidneys, suprarenal capsules, and great vessels. (Hepatic veins labeled at center top.) ICD 10 I …   Wikipedia

  • Nutcracker syndrome — Classification and external resources The nutcracker syndrome results from compression of the left renal vein between the aorta and the superior mesenteric artery. DiseasesDB …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”