TRPA is a family of transient receptor potential ion channels.

The sole member of the TRPA sub-family, TRPA1, contains 14 N-terminal ankyrin repeats and is believed to function as a mechanical stress sensor. It is expressed in the dorsal root ganglion, trigeminal ganglion, and hair cells. The temperature sensitivity of TRPA1 is highly disputed, with some reports claiming that it is activated by noxiously cold stimuli and others disputing such a claim. TRPA1 is known to be activated by isothiocyanates, which are the pungent chemicals in substances such as mustard oil and wasabi, methyl salicylate in winter green oil, and cinnamaldehyde in cinnamon, amongst numerous other substances.cite journal |author=Nilius B, Owsianik G, Voets T, Peters JA |title=Transient receptor potential cation channels in disease |journal=Physiol. Rev. |volume=87 |issue=1 |pages=165–217 |year=2007 |pmid=17237345 |doi=10.1152/physrev.00021.2006]

References

External links

Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

TRPA — can refer to: * Tahoe Regional Planning Agency * TRPA (channel) … Wikipedia
Ion channel — Not to be confused with: Ion Television or Ion implantation. Schematic diagram of an ion channel. 1 channel domains (typically four per channel), 2 outer vestibule, 3 selectivity filter, 4 diameter of selectivity filter, 5 phosphorylation site, 6 … Wikipedia
transient receptor potential channel — ▪ biology also called TRP channel superfamily of ion channels occurring in cell membranes (cell) that are involved in various types of sensory reception (senses), including thermoreception, chemoreception, mechanoreception, and photoreception … Universalium
Potassium channel — Top view of potassium ions (purple) moving through potassium channel (PDB 1BL8) In the field of cell biology, potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms … Wikipedia
BK channel — KCNMA1 The domain structure of BK channels Identifiers Symbol KCNMA1 Alt. symbols SLO … Wikipedia
Cyclic nucleotide-gated ion channel — Cyclic nucleotide gated (CNG) ion channels are ion channels that function in response to the binding of cyclic nucleotides. CNG channels are nonselective cation channels that are found in the membranes of various types of cells. Signal… … Wikipedia
Voltage-dependent calcium channel — Voltage dependent calcium channels (VDCC) are a group of voltage gated ion channels found in excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the ion Ca2+.[1][2] These channels are slightly permeable to sodium… … Wikipedia
Sodium channel — Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell s plasma membrane.[1][2] They are classified according to the trigger that opens the channel for such ions, i.e. either a voltage… … Wikipedia
Voltage-gated potassium channel — Ion channel (eukariotic) Potassium channel, structure in a membrane like environment. Calculated hydrocarbon boundaries of the lipid bilayer are indicated by red and blue dots. Identifiers Symbol Ion trans … Wikipedia
N-type calcium channel — Calcium channel, voltage dependent, N type, alpha 1B subunit Identifiers Symbols CACNA1B; BIII; CACNL1A5; CACNN; Cav2.2 External IDs … Wikipedia

Academic Dictionaries and Encyclopedias

TRPA (channel)

Look at other dictionaries:

Share the article and excerpts

Academic Dictionaries and Encyclopedias

Wikipedia

TRPA (channel)

Look at other dictionaries:

Share the article and excerpts

Direct link