Wogonin

Wogonin[1]
IUPAC name 5,7-Dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one
Other names Vogonin Norwogonin 8-methyl ether 5,7-dihydroxy-8-methoxyflavone
Identifiers
CAS number	632-85-9 Y
PubChem	5281703
ChEMBL	CHEMBL16171 N
Jmol-3D images	Image 1
SMILES COC1=C(C=C(C2=C1OC(=CC2=O)C3=CC=CC=C3)O)O
Properties
Molecular formula	C16H12O5
Molar mass	284.26 g mol−1
Exact mass	284.068473
Melting point	203-206 °C
N (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Wogonin is an O-methylated flavone, a flavonoid-like chemical compound which was found in Scutellaria baicalensis^[2] The glycosides of wogonin are known as wogonosides. For example, oroxindin is a wogonin glucuronide isolated from Oroxylum indicum.^[3] It is one of the active ingredients of Sho-Saiko-To, a Japanese herbal supplement believed to enhance liver health.

Wogonin has been found in one study to have anxiolytic properties in mice at doses of 7.5 to 30 mg/kg, without exhibiting the sedative and muscle-relaxing properties of benzodiazepines.

References

1. ^ Wogonin at chemblink.com
2. ^ Hui KM, Huen MS, Wang HY, et al (November 2002). "Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi". Biochem. Pharmacol. 64 (9): 1415–24. doi:10.1016/S0006-2952(02)01347-3. PMID 12392823. http://linkinghub.elsevier.com/retrieve/pii/S0006295202013473. 
3. ^ Oroxindin—A new flavone glucuronide from Oroxylum indicum. doi:10.1007/BF02844710. http://www.springerlink.com/content/dn4mwx7805167353. 

This article about a natural phenol is a stub. You can help Wikipedia by expanding it.v · Categories: Flavones Phenol ethers Resorcinols Natural phenol stubs Wikimedia Foundation. 2010. Игры ⚽ Нужна курсовая? Norwichtown Historic District Norwood, Albemarle County, Virginia Look at other dictionaries: Wogonin — Strukturformel Allgemeines Name Wogonin Andere Namen 5,7 …   Deutsch Wikipedia Wogonine — Général Nom IUPAC 5,7 dihydroxy 8 méhtoxy 2 phénylchromèn 4 one Synonymes Vogonine …   Wikipédia en Français Oroxindin — IUPAC name 5 Hydroxy 8 methoxy 7 O β D glucopyranuronosyl flavone …   Wikipedia Oroxylin A — IUPAC name 5,7 dihydroxy 6 methoxy 2 phenylchromen 4 one …   Wikipedia Luteolin — IUPAC name 2 (3,4 Dihydroxyphenyl) 5,7 dihydroxy 4 chromenone …   Wikipedia Diosmin — Systematic (IUPAC) name 5 Hydroxy 2 (3 hydroxy 4 methoxyphenyl) 7 [(2S,3R,4S,5S,6R) 3,4,5 trihydroxy 6 [[(2R,3R,4R,5R,6S) 3,4,5 trihydroxy 6 methyloxan 2 yl]oxymethyl]oxan 2 yl]oxychromen 4 one …   Wikipedia Chrysin — IUPAC name 5,7 dihydroxy 2 phenyl 4H chromen 4 one …   Wikipedia Scutellaria lateriflora — Taxobox name = Scutellaria lateriflora color = lightgreen regnum = Plantae divisio = Magnoliophyta classis = Magnoliopsida ordo = Lamiales familia = Lamiaceae genus = Scutellaria species = S. lateriflora binomial = Scutellaria lateriflora… …   Wikipedia Scutellaria galericulata — Taxobox | name = Common Skullcap regnum = Plantae divisio = Magnoliophyta classis = Magnoliopsida ordo = Lamiales familia = Lamiaceae genus = Scutellaria species = S. galericulata binomial = Scutellaria galericulata Common Skullcap ( Scutellaria… …   Wikipedia Hidrosmin — Systematic (IUPAC) name 5 (2 hydroxyethoxy) 2 (3 hydroxy 4 methoxyphenyl) 7 [(2S,3R,4S,5S,6R) 3,4,5 trihydroxy 6 [ [(2R,3R,4R,5R,6S) 3,4,5 trihydroxy 6 methyloxan 2 yl]oxymethyl]oxan 2 yl]oxychromen 4 one …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”