Cytochrome c Nitrite Reductase

Cytochrome c Nitrite Reductase
Identifiers
EC number	1.7.2.2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

Cytochrome c Nitrite Reductase (EC 1.7.2.2) is an enzyme that catalyzes the six electron reduction of nitrite to ammonia; an important step in the biological nitrogen cycle.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with a cytochrome as acceptor. The systematic name of this enzyme class is ammonia:ferricytochrome-c oxidoreductase. Other names in common use include cytochrome c nitrite reductase, and multiheme nitrite reductase. This enzyme participates in nitrogen metabolism.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1OAH, 2E80, and 2E81.

References

• R, Kroneck PM; Messerschmidt, A; Stach, P; Bourenkov, GP; Bartunik, HD; Huber, R; Kroneck, PM (1999). "Structure of cytochrome c nitrite reductase". Nature. 400 (6743): 476–80. doi:10.1038/22802. PMID 10440380. 

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