Nitrite reductase (cytochrome; ammonia-forming)

In enzymology, a nitrite reductase (cytochrome; ammonia-forming) (EC number|1.7.2.2) is an enzyme that catalyzes the chemical reaction

:NH₃ + 2 H₂O + 6 ferricytochrome c $ightleftharpoons$ nitrite + 6 ferrocytochrome c + 7 H⁺

The 3 substrates of this enzyme are NH₃, H₂O, and ferricytochrome c, whereas its 3 products are nitrite, ferrocytochrome c, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with a cytochrome as acceptor. The systematic name of this enzyme class is ammonia:ferricytochrome-c oxidoreductase. Other names in common use include cytochrome c nitrite reductase, and multiheme nitrite reductase. This enzyme participates in nitrogen metabolism.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1OAH, PDB link|2E80, and PDB link|2E81.

References

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External links

Gene Ontology (GO) codes