Methyl hydroxychalcone

Methyl hydroxychalcone
Methyl hydroxychalcone
Chemical structure of methyl hydroxychalcone
IUPAC name
(E)-3-(3-hydroxyphenyl)-1-(3-methylphenyl)prop-2-en-1-one
Other names
MCHP
3'-Methyl-3-hydroxychalcone
Identifiers
CAS number 153976-41-1
PubChem 6440383
Jmol-3D images Image 1
Properties
Molecular formula C16H14O2
Molar mass 238.28 g/mol
Exact mass 238.09938 u
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Methyl hydroxychalcone is a chalconoid found in cinnamon. It was thought to be an insulin mimetic, improving insulin response of diabetics.[1] It has since been determined that a flavonoid (cinnamtannin B1) is responsible for the insulin-like biological activity.[2]

See also

References

  1. ^ Anderson; A; G (August 1, 2001). "A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes". J Am Coll Nutr. 20 (4): 327–36. PMID 11506060. http://www.jacn.org/cgi/content/full/20/4/327. Retrieved 2008-06-19. 
  2. ^ Anderson; Broadhurst, CL; Polansky, MM; Schmidt, WF; Khan, A; Flanagan, VP; Schoene, NW; Graves, DJ (January 2004). "Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity". J Agric Food Chem. 52 (1): 65–70. doi:10.1021/jf034916b. PMID 14709014. 


v · glycosides
Chalconoids:
Butein | Isoliquiritigenin | Methyl hydroxychalcone | Okanin
Chalconoid glycosides:
Carthamin | Marein | okanin 3,4,3′-trimethyl ether 4′-glucoside | okanin 4-methyl ether 4′-glucoside | okanin 4-methyl ether 4′-glucoside monoacetate | Okanin 3,4-dimethyl ether 4′-glucoside
Acetylated chalconoids:
Licochalcone A | Sophoradin (prenylated) | Xanthohumol (prenylated)
O-methylated chalconoids
Cardamomin | Okanin 3,4,3′,4′-tetramethyl ether
Flavokavains
Flavokavain A | Flavokavain B | Flavokavain C
Synthetic
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