Cinnamtannin B1

Cinnamtannin B1
Cinnamtannin B1
Chemical structure of cinnamtannin B1
Identifiers
Jmol-3D images Image 1
Properties
Molecular formula C45H36O18
Molar mass 864.75 g/mol
Exact mass 864.190164 u
 YesY B1 (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Cinnamtannin B1 is a condensed tannin found in Cinnamomum verum. It is a type A proanthocyanidin.[1]

Cinnamon could have some pharmacological effects in the treatment of type 2 diabetes mellitus and insulin resistance. The plant material used in the study was mostly from Chinese cinnamon (see Chinese cinnamon's medicinal uses).[2][3] Recent studies in phytochemistry have indicated that cinnamtannin B1 isolated from C. Verum bears possible therapeutic effect on type 2 diabetes,[4] with the exception of the postmenopausal patients studied on C. Cassia.[5]

References

  1. ^ Anderson; Broadhurst, CL; Polansky, MM; Schmidt, WF; Khan, A; Flanagan, VP; Schoene, NW; Graves, DJ (January 2004). "Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity". J Agric Food Chem. 52 (1): 65–70. doi:10.1021/jf034916b. PMID 14709014. 
  2. ^ Khan A, Safdar M, Ali Khan MM, Khattak KN, Anderson RA (December 2003). "Cinnamon improves glucose and lipids of people with type 2 diabetes". Diabetes Care 26 (12): 3215–8. doi:10.2337/diacare.26.12.3215. PMID 14633804. http://care.diabetesjournals.org/cgi/pmidlookup?view=long&pmid=14633804. 
  3. ^ Verspohl, Eugen J. et al.; Bauer, K; Neddermann, E (2005). "Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum In vivo and In vitro". Phytotherapy Research 19 (3): 203–206. doi:10.1002/ptr.1643. PMID 15934022. 
  4. ^ Taher, Muhammad et al.. "A proanthocyanidin from Cinnamomum zeylanicum stimulates phosphorylation of insullin receptor in 3T3-L1 adipocyties" (PDF). http://eprints.utm.my/3661/1/JTJun44F%5B5%5D_FADZILAH_ADIBAH.pdf. Retrieved 2008-05-11. 
  5. ^ Vanschoonbeek, Kristof et al.. "Cinnamon Supplementation Does Not Improve Glycemic Control in Postmenopausal Type 2 Diabetes Patients". http://jn.nutrition.org/cgi/content/abstract/136/4/977. Retrieved 2008-05-11.