Mangiferin

Mangiferin
Mangiferin
Chemical structure of mangiferin
IUPAC name
1,3,6,7-tetrahydroxy-2-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one
Identifiers
CAS number 4773-96-0 YesY=
PubChem 5281647
UNII 1M84LD0UMD N
ChEMBL CHEMBL455364 N
Jmol-3D images Image 1
Properties
Molecular formula C19H18O11
Molar mass 422.33 g/mol
Exact mass 422.084911 u
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Mangiferin is a xanthonoid, a chemical compound found in mangoes and in Anemarrhena asphodeloides rhizomes.[1]

This molecule is a natural phenol and shows antimicrobial and antioxidant activities.[2] It shows inhibitory effects on type II 5α-reductase in vitro[3] It shows gastroprotective[4] and antidiabetic[1] effects in rodents.

References

  1. ^ a b Antidiabetic activity of a xanthone compound, mangiferin. Toshihiro Miura, Hiroyuki Ichiki, Itsuko Hashimoto, Naoki Iwamoto, Motoshi Kato, Masayoshi Kubo, Eriko Ishihara, Yasuhiro Komatsu, Minoru Okada, Torao Ishida and Keiichro Tanigawa, Phytomedicine, 2001, Vol. 8(2), pp. 85–87
  2. ^ Antimicrobial and antioxidant activity of the polyphenol mangiferin. I. Sto Ilova, S. Gargova, A. Sto Yano Va, L. Ho, Herba Polonica, Vol. 51 No 1/2 2005
  3. ^ Establishment of a novel model for studying the effects of extracts of Chinese herb medicine on human type II 5α-reductase in vitro Wang X., Liao J., Yin D., Zhan F., Dai S., Xie G., Sang X. Yakugaku Zasshi 2010 130:9 (1207-1214)
  4. ^ Gastroprotective Effect of Mangiferin, a Xanthonoid from Mangifera indica, against Gastric Injury Induced by Ethanol and Indomethacin in Rodents., Carvalho, A.C.S. Guedes, M.M. de Souza, A.L. Trevisan, M.T.S. Lima, A.F. Santos, F.A. Rao, V.S.N., Planta Mdecica, 2007, VOL 73; NUMB 13, pages 1372-1376
v · xanthonoids
Aglycones
Apetalinone A, B, C and D | Bellidifolin | Calozeyloxanthone | Desoxygambogenin | Desoxymorellin | Euxanthone | Forbesione | Gambogellic acid | Gambogenic acid | Gambogenin | Gambogenin dimethyl acetal | Gambogic acid | Gambogin | Gaudichaudiic acid A, B, C, D and E | Gaudichaudione A, B, C, D, E, F, G and H | Hanburin | Isogambogenin | Isomorellin | Isomoreollin B | Methylswertianin | Morellic acid | Morellin dimethyl acetal | Moreollic acid | Psorospermin | 2,3′,4,6-tetrahydroxybenzophenone | Tomentonone | Zeyloxanthonone
Glycosides
Indian yellow | Mangiferin | Mangostin-3,6-di-O-glucoside | Wubangziside A | Wubangziside B
Acetylated
Misc.
Gartanin | 8-disoxygartanin | Normangostin


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